A new approach to the development of a reusable piezoelectric crystal biosensor

E. Prusak-Sochaczewski; J. H.T. Luong

doi:10.1080/00032719008052452

A new approach to the development of a reusable piezoelectric crystal biosensor

E. Prusak-Sochaczewski
, J. H.T. Luong

National Research Council of Canada

Research output: Contribution to journal › Article › peer-review

Abstract

A reusable piezoelectric crystal immunosensor for human albumin has been developed. The crystal was coated with protein A and then reacted with anti-human albumin antibody. Human albumin in the range 10^-4to 10^-1mg/ml could be detected by the system. Crystals were regenerated by saturation with albumin and subsequent binding of a new anti-albumin antibody layer. The albumin assay could be repeated up to 5 times using the same crystal.

Original language	English
Pages (from-to)	401-409
Number of pages	9
Journal	Analytical Letters
Volume	23
Issue number	3
DOIs	https://doi.org/10.1080/00032719008052452
Publication status	Published - 1 Mar 1990
Externally published	Yes

Keywords

albumin
antibody to human-albumin
Piezoelectric crystal
reusability

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10.1080/00032719008052452

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N2 - A reusable piezoelectric crystal immunosensor for human albumin has been developed. The crystal was coated with protein A and then reacted with anti-human albumin antibody. Human albumin in the range 10-4to 10-1mg/ml could be detected by the system. Crystals were regenerated by saturation with albumin and subsequent binding of a new anti-albumin antibody layer. The albumin assay could be repeated up to 5 times using the same crystal.

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KW - Piezoelectric crystal

KW - reusability

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A new approach to the development of a reusable piezoelectric crystal biosensor

Abstract

Keywords

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