A Novel Wireless, Wearable Potentiostat for On-Body Electrochemical Sensing

Wearable electrochemical sensing platforms are increasingly employed for on-body, continuous biomarker monitoring in sports and healthcare. However, most existing systems focus on isolated parameters, highlighting the need for multimodal sensing to better assess overall physiological status. In this work, a reconfigurable and wearable potentiostat is presented, which is designed to support multimodal sensor measurements. The system architecture combines dual AD5941 sensing chips, a compact low power consumption IoT controller (XIAO ESP32C3), and optional I2C extension modules for physiological signal acquisition. Preliminary functionality is demonstrated through a sweat-based glucose sensing application using a novel laser-induced graphene sensor. The modular architecture enables compatibility with a wide range of electrochemical transducers and sensing modalities. Future development will focus on full system integration, in-lab validation with human subjects, and expansion of physiological signal acquisition capabilities.