A psychological model of predictive factors of distress following long COVID

  • Sinead A. Brown
  • , Jessica Holland
  • , Keith Gaynor
  • , Jessica Bramham
  • , Fiadhnait O'Keeffe
  • , Susan O'Flanagan
  • , Stefano Savinelli
  • , Patrick Mallon
  • , Eoin Feeney
  • , Grace Kenny
  • , Kathleen McCann
  • , Christine Boyd

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Long COVID, described as “the continuation or development of new symptoms 3 months after the initial SARS-CoV-2 infection”, is estimated to affect at least 10–20 % of all cases of acute SARS-CoV-2 infection. Because of its novelty, information regarding the experience of Long COVID is still emerging. Methods: This study examines psychological distress in two long COVID populations, and their experience of fatigue, cognitive failures, experiential avoidance, rumination, and perceived injustice. Participants were recruited via a long COVID hospital clinic and online self-diagnosing samples. Participants completed a battery of scales to measure psychological distress, fatigue, cognitive dysfunction, avoidance and rumination behaviours and the experience of injustice. Results: It was found that the regression model tested accounted for a significant amount of the variance in psychological distress (R2 = 0.675). Cognitive failures, avoidance, rumination, and injustice experiences significantly contributed to the experience of psychological distress and a moderated mediation accounted for the effect of fatigue on psychological distress. Limitations: The self-report measures in this study did not include objective measures of symptom severity. Cross-sectional data collected at a single time-point may not capture the dynamic nature of long COVID symptoms. Conclusions: These findings identify contributing factors to the experience of psychological distress in the long COVID population, providing direction to explore supportive interventions.

Original languageEnglish
Pages (from-to)394-402
Number of pages9
JournalJournal of Affective Disorders
Volume373
DOIs
Publication statusPublished - 15 Mar 2025
Externally publishedYes

Keywords

  • Avoidance
  • Cognitive dysfunction
  • Fatigue
  • Injustice experience
  • Long-COVID
  • Psychological distress

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