A solid phantom recipe for biophotonics applications: A step towards anatomically correct 3D tissue phantoms

Sanathana Konugolu Venkata Sekar; Andrea Pacheco; Pierluigi Martella; Haiyang Li; Pranav Lanka; Antonio Pifferi; Stefan Andersson-Engels

doi:10.1117/12.2526867

A solid phantom recipe for biophotonics applications: A step towards anatomically correct 3D tissue phantoms

Sanathana Konugolu Venkata Sekar
, Andrea Pacheco
, Pierluigi Martella
, Haiyang Li
, Pranav Lanka
, Antonio Pifferi
, Stefan Andersson-Engels

University of Pavia
Northeastern University China
Polytechnic University of Milan
National Research Council of Italy

Research output: Chapter in Book/Report/Conference proceedings › Conference proceeding › peer-review

Abstract

We present a well-tested, broadband (600-1100 nm) characterized phantom recipe to manufacture tissue mimicking optical phantoms over a wider range of optical properties (absorption 0.1-1 cm^-1, reduced scattering 5-25 cm^-1) relevant to human organs. The results of various tests like linearity, reproducibility, homogeneity showed the phantom recipe is robust with less than 4 % coefficient of variation (CV). Finally, a non-scattering 3D phantom of the infant's torso was presented to project the futuristic aspect of our work that is to 3D print human organs of biomedical relevance.

Original language	English
Title of host publication	Diffuse Optical Spectroscopy and Imaging VII
Editors	Hamid Dehghani, Heidrun Wabnitz
Publisher	SPIE
ISBN (Electronic)	9781510628410
ISBN (Print)	9781510628397
DOIs	https://doi.org/10.1117/12.2526867
Publication status	Published - 2019
Event	Diffuse Optical Spectroscopy and Imaging VII 2019 - Munich, Germany Duration: 23 Jun 2019 → 25 Jun 2019

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	11074
ISSN (Print)	1605-7422

Conference

Conference	Diffuse Optical Spectroscopy and Imaging VII 2019
Country/Territory	Germany
City	Munich
Period	23/06/19 → 25/06/19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 9 Industry, Innovation, and Infrastructure

Keywords

3D phantoms
absorption
diffuse optics
infant
lung
near infrared spectroscopy
scattering
time domain
tissue mimicking phantoms

Access to Document

10.1117/12.2526867

Cite this

Konugolu Venkata Sekar, S., Pacheco, A., Martella, P., Li, H., Lanka, P., Pifferi, A., & Andersson-Engels, S. (2019). A solid phantom recipe for biophotonics applications: A step towards anatomically correct 3D tissue phantoms. In H. Dehghani, & H. Wabnitz (Eds.), Diffuse Optical Spectroscopy and Imaging VII Article 110741C (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11074). SPIE. https://doi.org/10.1117/12.2526867

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title = "A solid phantom recipe for biophotonics applications: A step towards anatomically correct 3D tissue phantoms",

abstract = "We present a well-tested, broadband (600-1100 nm) characterized phantom recipe to manufacture tissue mimicking optical phantoms over a wider range of optical properties (absorption 0.1-1 cm-1, reduced scattering 5-25 cm-1) relevant to human organs. The results of various tests like linearity, reproducibility, homogeneity showed the phantom recipe is robust with less than 4 \% coefficient of variation (CV). Finally, a non-scattering 3D phantom of the infant's torso was presented to project the futuristic aspect of our work that is to 3D print human organs of biomedical relevance.",

keywords = "3D phantoms, absorption, diffuse optics, infant, lung, near infrared spectroscopy, scattering, time domain, tissue mimicking phantoms",

author = "\{Konugolu Venkata Sekar\}, Sanathana and Andrea Pacheco and Pierluigi Martella and Haiyang Li and Pranav Lanka and Antonio Pifferi and Stefan Andersson-Engels",

note = "Publisher Copyright: {\textcopyright} 2019 SPIE.; Diffuse Optical Spectroscopy and Imaging VII 2019 ; Conference date: 23-06-2019 Through 25-06-2019",

year = "2019",

doi = "10.1117/12.2526867",

language = "English",

isbn = "9781510628397",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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}

Konugolu Venkata Sekar, S, Pacheco, A, Martella, P, Li, H, Lanka, P, Pifferi, A & Andersson-Engels, S 2019, A solid phantom recipe for biophotonics applications: A step towards anatomically correct 3D tissue phantoms. in H Dehghani & H Wabnitz (eds), Diffuse Optical Spectroscopy and Imaging VII., 110741C, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 11074, SPIE, Diffuse Optical Spectroscopy and Imaging VII 2019, Munich, Germany, 23/06/19. https://doi.org/10.1117/12.2526867

A solid phantom recipe for biophotonics applications: A step towards anatomically correct 3D tissue phantoms. / Konugolu Venkata Sekar, Sanathana; Pacheco, Andrea; Martella, Pierluigi et al.
Diffuse Optical Spectroscopy and Imaging VII. ed. / Hamid Dehghani; Heidrun Wabnitz. SPIE, 2019. 110741C (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 11074).

Research output: Chapter in Book/Report/Conference proceedings › Conference proceeding › peer-review

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AU - Konugolu Venkata Sekar, Sanathana

AU - Pacheco, Andrea

AU - Martella, Pierluigi

AU - Li, Haiyang

AU - Lanka, Pranav

AU - Pifferi, Antonio

AU - Andersson-Engels, Stefan

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N2 - We present a well-tested, broadband (600-1100 nm) characterized phantom recipe to manufacture tissue mimicking optical phantoms over a wider range of optical properties (absorption 0.1-1 cm-1, reduced scattering 5-25 cm-1) relevant to human organs. The results of various tests like linearity, reproducibility, homogeneity showed the phantom recipe is robust with less than 4 % coefficient of variation (CV). Finally, a non-scattering 3D phantom of the infant's torso was presented to project the futuristic aspect of our work that is to 3D print human organs of biomedical relevance.

AB - We present a well-tested, broadband (600-1100 nm) characterized phantom recipe to manufacture tissue mimicking optical phantoms over a wider range of optical properties (absorption 0.1-1 cm-1, reduced scattering 5-25 cm-1) relevant to human organs. The results of various tests like linearity, reproducibility, homogeneity showed the phantom recipe is robust with less than 4 % coefficient of variation (CV). Finally, a non-scattering 3D phantom of the infant's torso was presented to project the futuristic aspect of our work that is to 3D print human organs of biomedical relevance.

KW - 3D phantoms

KW - absorption

KW - diffuse optics

KW - infant

KW - lung

KW - near infrared spectroscopy

KW - scattering

KW - time domain

KW - tissue mimicking phantoms

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AN - SCOPUS:85076907679

SN - 9781510628397

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

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PB - SPIE

Y2 - 23 June 2019 through 25 June 2019

ER -

Konugolu Venkata Sekar S, Pacheco A, Martella P, Li H, Lanka P, Pifferi A et al. A solid phantom recipe for biophotonics applications: A step towards anatomically correct 3D tissue phantoms. In Dehghani H, Wabnitz H, editors, Diffuse Optical Spectroscopy and Imaging VII. SPIE. 2019. 110741C. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2526867

A solid phantom recipe for biophotonics applications: A step towards anatomically correct 3D tissue phantoms

Abstract

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UN SDGs

Keywords

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