Activation of the p38 MAPK and ERK1/2 pathways is required for Fas-induced IL-8 production in colonic epithelial cells

  • Darren O'Brien
  • , Terry O'Connor
  • , Fergus Shanahan
  • , Joe O'Connell

Research output: Contribution to journalArticlepeer-review

Abstract

This paper aims to examine the contribution of all three of the MAP kinase signaling pathways to Fas-induced IL-8 up-regulation in HT29 colon epithelial cells.

Original languageEnglish
Pages (from-to)161-165
Number of pages5
JournalAnnals of the New York Academy of Sciences
Volume973
DOIs
Publication statusPublished - 2002

Keywords

  • Extracellular signal-regulated kinase (ERK1/2)
  • Interleukin-8 (IL-8)
  • Mitogen-activated protein kinase (MAPK)

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