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Allergen immunotherapy for IgE-mediated food allergy: Protocol for a systematic review

  • Sangeeta Dhami
  • , Ulugbek Nurmatov
  • , Giovanni Battista Pajno
  • , Montserrat Fernandez-Rivas
  • , Antonella Muraro
  • , Graham Roberts
  • , Cezmi Akdis
  • , Montserrat Alvaro-Lozano
  • , Kirsten Beyer
  • , Carsten Bindslev-Jensen
  • , Wesley Burks
  • , George Du Toit
  • , Motohiro Ebisawa
  • , Philippe Eigenmann
  • , Edward Knol
  • , Mika Makela
  • , Kari Christine Nadeau
  • , Liam O'Mahony
  • , Nikolaos Papadopoulos
  • , Lars Poulsen
  • Cansin Sackesen, Hugh Sampson, Alexandra Santos, Ronald Van Ree, Frans Timmermans, Aziz Sheikh
  • Evidence-Based Health Care Ltd
  • Cardiff University
  • University of Messina
  • Hospital Clínico San Carlos de Madrid
  • Azienda Ospedaliera di Padova
  • University Hospital Southampton NHS Foundation Trust
  • University of Southampton
  • Swiss Institute of Allergy and Asthma Research
  • University of Barcelona
  • Charité – Universitätsmedizin Berlin
  • Icahn School of Medicine at Mount Sinai
  • University of Southern Denmark
  • University of North Carolina at Chapel Hill
  • Guy's and St Thomas' NHS Foundation Trust
  • National Hospital Organization Sagamihara National Hospital
  • University of Geneva
  • Utrecht University
  • Hospital District of Helsinki and Uusimaa
  • Stanford University
  • University of Zurich
  • National and Kapodistrian University of Athens
  • University of Copenhagen
  • Koc University
  • World Allergy Organization
  • Amsterdam University Medical Centers
  • Nederlands Anafylaxis Netwerk—European Anaphylaxis Taskforce
  • University of Edinburgh

Research output: Contribution to journalReview articlepeer-review

Abstract

Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy. Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. Discussion: The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.

Original languageEnglish
Article number24
JournalClinical and Translational Allergy
Volume6
Issue number1
DOIs
Publication statusPublished - 5 Jul 2016
Externally publishedYes

Keywords

  • Allergen immunotherapy
  • Allergy
  • Food allergy
  • Sensitisation
  • Therapy

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