TY - GEN
T1 - An improved statistical approach to the estimation of spatial bias and variability in reconstructed PET data
AU - Mou, T.
AU - Huang, J.
AU - Zhang, Y.
AU - Kinahan, P.
AU - O'Sullivan, F.
N1 - Publisher Copyright:
© 2015 IEEE.
PY - 2016/10/3
Y1 - 2016/10/3
N2 - THE spatial bias and covariance characteristics of reconstructed PET data are important as routine assessments of image quality in PET scanners [4], [5]. Our previous empirical analysis of uniform Phantom data across the 43 sites in ACRIN [2] shows that both spatial bias and covariance can be decomposed as a product of a trans-axial radial function and axial function [1]. On the basis of this decomposition, we develop a penalised maximum likelihood type approach for analysis of bias and variance patterns. This can be viewed as a variation on the Π-method of Brieman [3]. The proposed approach is evaluated using a simulation model and demonstrated on PET data collected on an operationally used clinical PET scanner with the dynamic Brain ACRIN imaging protocol [2].
AB - THE spatial bias and covariance characteristics of reconstructed PET data are important as routine assessments of image quality in PET scanners [4], [5]. Our previous empirical analysis of uniform Phantom data across the 43 sites in ACRIN [2] shows that both spatial bias and covariance can be decomposed as a product of a trans-axial radial function and axial function [1]. On the basis of this decomposition, we develop a penalised maximum likelihood type approach for analysis of bias and variance patterns. This can be viewed as a variation on the Π-method of Brieman [3]. The proposed approach is evaluated using a simulation model and demonstrated on PET data collected on an operationally used clinical PET scanner with the dynamic Brain ACRIN imaging protocol [2].
UR - https://www.scopus.com/pages/publications/84994166882
U2 - 10.1109/NSSMIC.2015.7582172
DO - 10.1109/NSSMIC.2015.7582172
M3 - Conference proceeding
AN - SCOPUS:84994166882
T3 - 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015
BT - 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2015 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2015
Y2 - 31 October 2015 through 7 November 2015
ER -