Abstract
Infectious diseases are among the most prominent threats to mankind. When preventive health care cannot be provided, a viable means of disease control is the isolation of individuals who may be infected. To study the impact of isolation, we propose a system of delay differential equations and offer our model analysis based on the geometric theory of semi-flows. Calibrating the response to an outbreak in terms of the fraction of infectious individuals isolated and the speed with which this is done, we deduce the minimum response required to curb an incipient outbreak, and predict the ensuing endemic state should the infection continue to spread.
| Original language | English |
|---|---|
| Pages (from-to) | 249-279 |
| Number of pages | 31 |
| Journal | Journal of Mathematical Biology |
| Volume | 79 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Jul 2019 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Delay differential equations
- Disease control via isolation
- Epidemic spreading
- Invariant manifolds
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