Abstract
This review discusses synthesis of enantiopure sulfoxides through the asymmetric oxidation of prochiral sulfides. The use of metal complexes to promote asymmetric sulfoxidation is described in detail, with a particular emphasis on the synthesis of biologically active sulfoxides. The use of non-metal-based systems, such as oxaziridines, chiral hydroperoxides and peracids, as well as enzyme-catalyzed sulfoxidations is also examined.
| Original language | English |
|---|---|
| Pages (from-to) | 301-341 |
| Number of pages | 41 |
| Journal | Journal of Sulfur Chemistry |
| Volume | 34 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1 Jun 2013 |
Keywords
- asymmetric synthesis
- enantioselective synthesis
- metal-based catalysts
- sulfide oxidation
- sulfoxides