Atypical p-ANCA is not a poor prognostic marker in postinfectious glomerulonephritis

Aoife Waters; Valerie Langlois; Paul Thorner; Denis Geary

doi:10.1007/s00467-007-0495-1

Atypical p-ANCA is not a poor prognostic marker in postinfectious glomerulonephritis

Aoife Waters
, Valerie Langlois
, Paul Thorner
, Denis Geary

University of Toronto

Research output: Contribution to journal › Article › peer-review

Abstract

Postinfectious glomerulonephritis (PIGN) most commonly follows streptococcal infection. Antineutrophil cytoplasmic antibodies (ANCA) are characteristically negative in PIGN. We report on five cases who had positive atypical pANCA at presentation. The outcome was typical of other cases of PIGN with complete resolution of the glomerulonephritis in all five patients. Atypical pANCA occurs in a number of inflammatory conditions and antigenic targets may include proteins other than myeloperoxidase or proteinase 3. The presence of atypical p-ANCA does not indicate a poor prognosis.

Original language	English
Pages (from-to)	1383-1386
Number of pages	4
Journal	Pediatric Nephrology
Volume	22
Issue number	9
DOIs	https://doi.org/10.1007/s00467-007-0495-1
Publication status	Published - Sep 2007
Externally published	Yes

Keywords

Atypical p-antineutrophil cytoplasmic antibody
Outcome
Postinfectious glomerulonephritis

Access to Document

10.1007/s00467-007-0495-1

Cite this

@article{eddb2a1088cd464e8b4a2b393e959f60,

title = "Atypical p-ANCA is not a poor prognostic marker in postinfectious glomerulonephritis",

abstract = "Postinfectious glomerulonephritis (PIGN) most commonly follows streptococcal infection. Antineutrophil cytoplasmic antibodies (ANCA) are characteristically negative in PIGN. We report on five cases who had positive atypical pANCA at presentation. The outcome was typical of other cases of PIGN with complete resolution of the glomerulonephritis in all five patients. Atypical pANCA occurs in a number of inflammatory conditions and antigenic targets may include proteins other than myeloperoxidase or proteinase 3. The presence of atypical p-ANCA does not indicate a poor prognosis.",

keywords = "Atypical p-antineutrophil cytoplasmic antibody, Outcome, Postinfectious glomerulonephritis",

author = "Aoife Waters and Valerie Langlois and Paul Thorner and Denis Geary",

year = "2007",

month = sep,

doi = "10.1007/s00467-007-0495-1",

language = "English",

volume = "22",

pages = "1383--1386",

journal = "Pediatric Nephrology",

issn = "0931-041X",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "9",

}

TY - JOUR

T1 - Atypical p-ANCA is not a poor prognostic marker in postinfectious glomerulonephritis

AU - Waters, Aoife

AU - Langlois, Valerie

AU - Thorner, Paul

AU - Geary, Denis

PY - 2007/9

Y1 - 2007/9

N2 - Postinfectious glomerulonephritis (PIGN) most commonly follows streptococcal infection. Antineutrophil cytoplasmic antibodies (ANCA) are characteristically negative in PIGN. We report on five cases who had positive atypical pANCA at presentation. The outcome was typical of other cases of PIGN with complete resolution of the glomerulonephritis in all five patients. Atypical pANCA occurs in a number of inflammatory conditions and antigenic targets may include proteins other than myeloperoxidase or proteinase 3. The presence of atypical p-ANCA does not indicate a poor prognosis.

AB - Postinfectious glomerulonephritis (PIGN) most commonly follows streptococcal infection. Antineutrophil cytoplasmic antibodies (ANCA) are characteristically negative in PIGN. We report on five cases who had positive atypical pANCA at presentation. The outcome was typical of other cases of PIGN with complete resolution of the glomerulonephritis in all five patients. Atypical pANCA occurs in a number of inflammatory conditions and antigenic targets may include proteins other than myeloperoxidase or proteinase 3. The presence of atypical p-ANCA does not indicate a poor prognosis.

KW - Atypical p-antineutrophil cytoplasmic antibody

KW - Outcome

KW - Postinfectious glomerulonephritis

UR - https://www.scopus.com/pages/publications/34447332480

U2 - 10.1007/s00467-007-0495-1

DO - 10.1007/s00467-007-0495-1

M3 - Article

C2 - 17479299

AN - SCOPUS:34447332480

SN - 0931-041X

VL - 22

SP - 1383

EP - 1386

JO - Pediatric Nephrology

JF - Pediatric Nephrology

IS - 9

ER -

Atypical p-ANCA is not a poor prognostic marker in postinfectious glomerulonephritis

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this