Bacterial biosynthesis of a multipotent stilbene

Susan A. Joyce; Alexander O. Brachmann; Itamar Glazer; Lea Lango; Gertrud Schwär; David J. Clarke; Helge B. Bode

doi:10.1002/anie.200705148

Bacterial biosynthesis of a multipotent stilbene

Susan A. Joyce
, Alexander O. Brachmann
, Itamar Glazer
, Lea Lango
, Gertrud Schwär
, David J. Clarke
, Helge B. Bode

Research output: Contribution to journal › Article › peer-review

Abstract

(Chemical Equation Presented) Commuting between kingdoms: The biosynthesis of the only nonplant stilbene 1 from Photorhabdus bacteria has been solved by identification of all the genes involved in its biosynthesis and by feeding experiments. Stilbene 1 is derived from the condensation of two β-ketoacyl thioesters and is required for the normal development of Heterorhabditis nematodes, the natural host of Photorhabdus.

Original language	English
Pages (from-to)	1942-1945
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	47
Issue number	10
DOIs	https://doi.org/10.1002/anie.200705148
Publication status	Published - 22 Feb 2008

Keywords

Biosynthesis
Nematodes
Photorhabdus
Stilbenes
Symbiosis

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10.1002/anie.200705148

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abstract = "(Chemical Equation Presented) Commuting between kingdoms: The biosynthesis of the only nonplant stilbene 1 from Photorhabdus bacteria has been solved by identification of all the genes involved in its biosynthesis and by feeding experiments. Stilbene 1 is derived from the condensation of two β-ketoacyl thioesters and is required for the normal development of Heterorhabditis nematodes, the natural host of Photorhabdus.",

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AU - Clarke, David J.

AU - Bode, Helge B.

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KW - Stilbenes

KW - Symbiosis

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Bacterial biosynthesis of a multipotent stilbene

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Keywords

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