TY - JOUR
T1 - Bacteriophages of the Order Crassvirales
T2 - What Do We Currently Know about This Keystone Component of the Human Gut Virome?
AU - Smith, Linda
AU - Goldobina, Ekaterina
AU - Govi, Bianca
AU - Shkoporov, Andrey N.
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/4
Y1 - 2023/4
N2 - The order Crassvirales comprises dsDNA bacteriophages infecting bacteria in the phylum Bacteroidetes that are found in a variety of environments but are especially prevalent in the mammalian gut. This review summarises available information on the genomics, diversity, taxonomy, and ecology of this largely uncultured viral taxon. With experimental data available from a handful of cultured representatives, the review highlights key properties of virion morphology, infection, gene expression and replication processes, and phage-host dynamics.
AB - The order Crassvirales comprises dsDNA bacteriophages infecting bacteria in the phylum Bacteroidetes that are found in a variety of environments but are especially prevalent in the mammalian gut. This review summarises available information on the genomics, diversity, taxonomy, and ecology of this largely uncultured viral taxon. With experimental data available from a handful of cultured representatives, the review highlights key properties of virion morphology, infection, gene expression and replication processes, and phage-host dynamics.
KW - Crassvirales
KW - human gut microbiome
KW - metagenomics
KW - virome
UR - https://www.scopus.com/pages/publications/85156088118
U2 - 10.3390/biom13040584
DO - 10.3390/biom13040584
M3 - Review article
C2 - 37189332
AN - SCOPUS:85156088118
SN - 2218-273X
VL - 13
JO - Biomolecules
JF - Biomolecules
IS - 4
M1 - 584
ER -