TY - JOUR
T1 - Bifidobacterium asteroides PRL2011 Genome Analysis Reveals Clues for Colonization of the Insect Gut
AU - Bottacini, Francesca
AU - Milani, Christian
AU - Turroni, Francesca
AU - Sánchez, Borja
AU - Foroni, Elena
AU - Duranti, Sabrina
AU - Serafini, Fausta
AU - Viappiani, Alice
AU - Strati, Francesco
AU - Ferrarini, Alberto
AU - Delledonne, Massimo
AU - Henrissat, Bernard
AU - Coutinho, Pedro
AU - Fitzgerald, Gerald F.
AU - Margolles, Abelardo
AU - van Sinderen, Douwe
AU - Ventura, Marco
PY - 2012/9/20
Y1 - 2012/9/20
N2 - Bifidobacteria are known as anaerobic/microaerophilic and fermentative microorganisms, which commonly inhabit the gastrointestinal tract of various animals and insects. Analysis of the 2,167,301 bp genome of Bifidobacterium asteroides PRL2011, a strain isolated from the hindgut of Apis mellifera var. ligustica, commonly known as the honey bee, revealed its predicted capability for respiratory metabolism. Conservation of the latter gene clusters in various B. asteroides strains enforces the notion that respiration is a common metabolic feature of this ancient bifidobacterial species, which has been lost in currently known mammal-derived Bifidobacterium species. In fact, phylogenomic based analyses suggested an ancient origin of B. asteroides and indicates it as an ancestor of the genus Bifidobacterium. Furthermore, the B. asteroides PRL2011 genome encodes various enzymes for coping with toxic products that arise as a result of oxygen-mediated respiration.
AB - Bifidobacteria are known as anaerobic/microaerophilic and fermentative microorganisms, which commonly inhabit the gastrointestinal tract of various animals and insects. Analysis of the 2,167,301 bp genome of Bifidobacterium asteroides PRL2011, a strain isolated from the hindgut of Apis mellifera var. ligustica, commonly known as the honey bee, revealed its predicted capability for respiratory metabolism. Conservation of the latter gene clusters in various B. asteroides strains enforces the notion that respiration is a common metabolic feature of this ancient bifidobacterial species, which has been lost in currently known mammal-derived Bifidobacterium species. In fact, phylogenomic based analyses suggested an ancient origin of B. asteroides and indicates it as an ancestor of the genus Bifidobacterium. Furthermore, the B. asteroides PRL2011 genome encodes various enzymes for coping with toxic products that arise as a result of oxygen-mediated respiration.
UR - https://www.scopus.com/pages/publications/84866673240
U2 - 10.1371/journal.pone.0044229
DO - 10.1371/journal.pone.0044229
M3 - Article
C2 - 23028506
AN - SCOPUS:84866673240
SN - 1932-6203
VL - 7
JO - PLOS ONE
JF - PLOS ONE
IS - 9
M1 - e44229
ER -