Biopharmaceutical development, production, and quality

Brahim Benyahia; Larissa Pereira Brumano; Adalberto Pessoa; Francisco Vitor Santos da Silva

doi:10.1016/B978-0-444-64301-8.00003-2

Biopharmaceutical development, production, and quality

Brahim Benyahia
, Larissa Pereira Brumano
, Adalberto Pessoa
, Francisco Vitor Santos da Silva

Loughborough University
Universidade de São Paulo

Research output: Chapter in Book/Report/Conference proceedings › Chapter › peer-review

Abstract

The present chapter continues the description of the pharmaceutical applications of biomolecules that was started in the previous one. However, here we shift our focus onto production and design strategies. We begin by presenting different biopharmaceutical processing technologies, highlighting the role of continuous manufacturing and molecular biology tools in improving production yield and quality. Finally, prompted by the recent advances of the pharmaceutical sector, we provide the reader with a road map for implementing “Quality-by-Design” in the development of biopharmaceuticals.

Original language	English
Title of host publication	New and Future Developments in Microbial Biotechnology and Bioengineering
Subtitle of host publication	Microbial Biomolecules: Properties, Relevance, and Their Translational Applications
Publisher	Elsevier
Pages	69-89
Number of pages	21
ISBN (Electronic)	9780444643018
DOIs	https://doi.org/10.1016/B978-0-444-64301-8.00003-2
Publication status	Published - 1 Jan 2020
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 9 Industry, Innovation, and Infrastructure

Keywords

Continuous production
Downstream processing
Molecular biology
Quality-by-Design
Upstream processing

Access to Document

10.1016/B978-0-444-64301-8.00003-2

Cite this

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title = "Biopharmaceutical development, production, and quality",

abstract = "The present chapter continues the description of the pharmaceutical applications of biomolecules that was started in the previous one. However, here we shift our focus onto production and design strategies. We begin by presenting different biopharmaceutical processing technologies, highlighting the role of continuous manufacturing and molecular biology tools in improving production yield and quality. Finally, prompted by the recent advances of the pharmaceutical sector, we provide the reader with a road map for implementing “Quality-by-Design” in the development of biopharmaceuticals.",

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author = "Brahim Benyahia and Brumano, \{Larissa Pereira\} and Adalberto Pessoa and \{Santos da Silva\}, \{Francisco Vitor\}",

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doi = "10.1016/B978-0-444-64301-8.00003-2",

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Biopharmaceutical development, production, and quality. / Benyahia, Brahim; Brumano, Larissa Pereira; Pessoa, Adalberto et al.
New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biomolecules: Properties, Relevance, and Their Translational Applications. Elsevier, 2020. p. 69-89.

Research output: Chapter in Book/Report/Conference proceedings › Chapter › peer-review

TY - CHAP

T1 - Biopharmaceutical development, production, and quality

AU - Benyahia, Brahim

AU - Brumano, Larissa Pereira

AU - Pessoa, Adalberto

AU - Santos da Silva, Francisco Vitor

PY - 2020/1/1

Y1 - 2020/1/1

N2 - The present chapter continues the description of the pharmaceutical applications of biomolecules that was started in the previous one. However, here we shift our focus onto production and design strategies. We begin by presenting different biopharmaceutical processing technologies, highlighting the role of continuous manufacturing and molecular biology tools in improving production yield and quality. Finally, prompted by the recent advances of the pharmaceutical sector, we provide the reader with a road map for implementing “Quality-by-Design” in the development of biopharmaceuticals.

AB - The present chapter continues the description of the pharmaceutical applications of biomolecules that was started in the previous one. However, here we shift our focus onto production and design strategies. We begin by presenting different biopharmaceutical processing technologies, highlighting the role of continuous manufacturing and molecular biology tools in improving production yield and quality. Finally, prompted by the recent advances of the pharmaceutical sector, we provide the reader with a road map for implementing “Quality-by-Design” in the development of biopharmaceuticals.

KW - Continuous production

KW - Downstream processing

KW - Molecular biology

KW - Quality-by-Design

KW - Upstream processing

UR - https://www.scopus.com/pages/publications/85124925278

U2 - 10.1016/B978-0-444-64301-8.00003-2

DO - 10.1016/B978-0-444-64301-8.00003-2

M3 - Chapter

AN - SCOPUS:85124925278

SP - 69

EP - 89

BT - New and Future Developments in Microbial Biotechnology and Bioengineering

PB - Elsevier

ER -

Biopharmaceutical development, production, and quality

Abstract

UN SDGs

Keywords

Access to Document

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