Casein-derived antimicrobial peptides generated by Lactobacillus acidophilus DPC6026

M. Hayes; R. P. Ross; G. F. Fitzgerald; C. Hill; C. Stanton

doi:10.1128/AEM.72.3.2260-2264.2006

Casein-derived antimicrobial peptides generated by Lactobacillus acidophilus DPC6026

M. Hayes
, R. P. Ross
, G. F. Fitzgerald
, C. Hill
, C. Stanton

Research output: Contribution to journal › Article › peer-review

Abstract

Three peptides produced by a Lactobacillus acidophilus DPC6026 fermentation of sodium caseinate and showing antibacterial activity against pathogenic strains Enterobacter sakazakii ATCC 12868 and Escherichia coli DPC5063 were characterized. These peptides were all generated from bovine α_s1-casein and identified as IKHQGLPQE, VLNENLLR, and SDIPNPIGSENSEK. These peptides may have bioprotective applicability and potential use in milk-based formula, which has been linked to E. sakazakii infection in neonates.

Original language	English
Pages (from-to)	2260-2264
Number of pages	5
Journal	Applied and Environmental Microbiology
Volume	72
Issue number	3
DOIs	https://doi.org/10.1128/AEM.72.3.2260-2264.2006
Publication status	Published - Mar 2006

Access to Document

10.1128/AEM.72.3.2260-2264.2006

Cite this

@article{f5817a8e401f4068aad3c09557f43fef,

title = "Casein-derived antimicrobial peptides generated by Lactobacillus acidophilus DPC6026",

abstract = "Three peptides produced by a Lactobacillus acidophilus DPC6026 fermentation of sodium caseinate and showing antibacterial activity against pathogenic strains Enterobacter sakazakii ATCC 12868 and Escherichia coli DPC5063 were characterized. These peptides were all generated from bovine αs1-casein and identified as IKHQGLPQE, VLNENLLR, and SDIPNPIGSENSEK. These peptides may have bioprotective applicability and potential use in milk-based formula, which has been linked to E. sakazakii infection in neonates.",

author = "M. Hayes and Ross, \{R. P.\} and Fitzgerald, \{G. F.\} and C. Hill and C. Stanton",

year = "2006",

month = mar,

doi = "10.1128/AEM.72.3.2260-2264.2006",

language = "English",

volume = "72",

pages = "2260--2264",

journal = "Applied and Environmental Microbiology",

issn = "0099-2240",

publisher = "American Society for Microbiology",

number = "3",

}

TY - JOUR

T1 - Casein-derived antimicrobial peptides generated by Lactobacillus acidophilus DPC6026

AU - Hayes, M.

AU - Ross, R. P.

AU - Fitzgerald, G. F.

AU - Hill, C.

AU - Stanton, C.

PY - 2006/3

Y1 - 2006/3

N2 - Three peptides produced by a Lactobacillus acidophilus DPC6026 fermentation of sodium caseinate and showing antibacterial activity against pathogenic strains Enterobacter sakazakii ATCC 12868 and Escherichia coli DPC5063 were characterized. These peptides were all generated from bovine αs1-casein and identified as IKHQGLPQE, VLNENLLR, and SDIPNPIGSENSEK. These peptides may have bioprotective applicability and potential use in milk-based formula, which has been linked to E. sakazakii infection in neonates.

AB - Three peptides produced by a Lactobacillus acidophilus DPC6026 fermentation of sodium caseinate and showing antibacterial activity against pathogenic strains Enterobacter sakazakii ATCC 12868 and Escherichia coli DPC5063 were characterized. These peptides were all generated from bovine αs1-casein and identified as IKHQGLPQE, VLNENLLR, and SDIPNPIGSENSEK. These peptides may have bioprotective applicability and potential use in milk-based formula, which has been linked to E. sakazakii infection in neonates.

UR - https://www.scopus.com/pages/publications/33644935211

U2 - 10.1128/AEM.72.3.2260-2264.2006

DO - 10.1128/AEM.72.3.2260-2264.2006

M3 - Article

C2 - 16517684

AN - SCOPUS:33644935211

SN - 0099-2240

VL - 72

SP - 2260

EP - 2264

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 3

ER -

Casein-derived antimicrobial peptides generated by Lactobacillus acidophilus DPC6026

Abstract

Access to Document

Other files and links

Fingerprint

Cite this