Communication between gastrointestinal bacteria and the nervous system

  • Javier A. Bravo
  • , Marcela Julio-Pieper
  • , Paul Forsythe
  • , Wolfgang Kunze
  • , Timothy G. Dinan
  • , John Bienenstock
  • , John F. Cryan

Research output: Contribution to journalReview articlepeer-review

Abstract

In the past few years, intestinal microbiota has emerged as a novel target for the treatment of gut-brain axis alterations. These include functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), which can be comorbid with stress-related psychiatric conditions. Thus, modulation of the microbiota (e.g. with the use of probiotics) could be proposed as a novel strategy not only for the treatment of IBS but also as an adjuvant for psychiatric treatment of anxiety and depression.

Original languageEnglish
Pages (from-to)667-672
Number of pages6
JournalCurrent Opinion in Pharmacology
Volume12
Issue number6
DOIs
Publication statusPublished - Dec 2012

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