TY - JOUR
T1 - Comparative genomics of Bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon
AU - Milani, Christian
AU - Duranti, Sabrina
AU - Lugli, Gabriele Andrea
AU - Bottacini, Francesca
AU - Strati, Francesco
AU - Arioli, Stefania
AU - Foroni, Elena
AU - Turroni, Francesca
AU - van Sinderen, Douwe
AU - Ventura, Marco
PY - 2013/7
Y1 - 2013/7
N2 - Strains of Bifidobacterium animalis subsp. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. In this article, we describe the complete genetic makeup of the B. animalis subsp. lactis Bl12 genome and discuss the genetic relatedness of this strain with other sequenced strains belonging to this taxon. Moreover, a detailed comparative genomic analysis of B. animalis subsp. lactis genomes was performed, which revealed a closely related and isogenic nature of all currently available B. animalis subsp. lactis strains, thus strongly suggesting a closed pan-genome structure of this bacterial group.
AB - Strains of Bifidobacterium animalis subsp. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. In this article, we describe the complete genetic makeup of the B. animalis subsp. lactis Bl12 genome and discuss the genetic relatedness of this strain with other sequenced strains belonging to this taxon. Moreover, a detailed comparative genomic analysis of B. animalis subsp. lactis genomes was performed, which revealed a closely related and isogenic nature of all currently available B. animalis subsp. lactis strains, thus strongly suggesting a closed pan-genome structure of this bacterial group.
UR - https://www.scopus.com/pages/publications/84879824186
U2 - 10.1128/AEM.00984-13
DO - 10.1128/AEM.00984-13
M3 - Article
C2 - 23645200
AN - SCOPUS:84879824186
SN - 0099-2240
VL - 79
SP - 4304
EP - 4315
JO - Applied and Environmental Microbiology
JF - Applied and Environmental Microbiology
IS - 14
ER -