Comparative genomics of Bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon

Christian Milani; Sabrina Duranti; Gabriele Andrea Lugli; Francesca Bottacini; Francesco Strati; Stefania Arioli; Elena Foroni; Francesca Turroni; Douwe van Sinderen; Marco Ventura

doi:10.1128/AEM.00984-13

Comparative genomics of Bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon

Christian Milani
, Sabrina Duranti
, Gabriele Andrea Lugli
, Francesca Bottacini
, Francesco Strati
, Stefania Arioli
, Elena Foroni
, Francesca Turroni
, Douwe van Sinderen
, Marco Ventura

University of Parma
University of Milan

Research output: Contribution to journal › Article › peer-review

Abstract

Strains of Bifidobacterium animalis subsp. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. In this article, we describe the complete genetic makeup of the B. animalis subsp. lactis Bl12 genome and discuss the genetic relatedness of this strain with other sequenced strains belonging to this taxon. Moreover, a detailed comparative genomic analysis of B. animalis subsp. lactis genomes was performed, which revealed a closely related and isogenic nature of all currently available B. animalis subsp. lactis strains, thus strongly suggesting a closed pan-genome structure of this bacterial group.

Original language	English
Pages (from-to)	4304-4315
Number of pages	12
Journal	Applied and Environmental Microbiology
Volume	79
Issue number	14
DOIs	https://doi.org/10.1128/AEM.00984-13
Publication status	Published - Jul 2013

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title = "Comparative genomics of Bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon",

abstract = "Strains of Bifidobacterium animalis subsp. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. In this article, we describe the complete genetic makeup of the B. animalis subsp. lactis Bl12 genome and discuss the genetic relatedness of this strain with other sequenced strains belonging to this taxon. Moreover, a detailed comparative genomic analysis of B. animalis subsp. lactis genomes was performed, which revealed a closely related and isogenic nature of all currently available B. animalis subsp. lactis strains, thus strongly suggesting a closed pan-genome structure of this bacterial group.",

author = "Christian Milani and Sabrina Duranti and Lugli, \{Gabriele Andrea\} and Francesca Bottacini and Francesco Strati and Stefania Arioli and Elena Foroni and Francesca Turroni and \{van Sinderen\}, Douwe and Marco Ventura",

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doi = "10.1128/AEM.00984-13",

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AU - Milani, Christian

AU - Duranti, Sabrina

AU - Lugli, Gabriele Andrea

AU - Bottacini, Francesca

AU - Strati, Francesco

AU - Arioli, Stefania

AU - Foroni, Elena

AU - Turroni, Francesca

AU - van Sinderen, Douwe

AU - Ventura, Marco

PY - 2013/7

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AB - Strains of Bifidobacterium animalis subsp. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. In this article, we describe the complete genetic makeup of the B. animalis subsp. lactis Bl12 genome and discuss the genetic relatedness of this strain with other sequenced strains belonging to this taxon. Moreover, a detailed comparative genomic analysis of B. animalis subsp. lactis genomes was performed, which revealed a closely related and isogenic nature of all currently available B. animalis subsp. lactis strains, thus strongly suggesting a closed pan-genome structure of this bacterial group.

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Comparative genomics of Bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon

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