Compatible solutes: The key to Listeria's success as a versatile gastrointestinal pathogen?

Roy D. Sleator; Colin Hill

doi:10.1186/1757-4749-2-20

Compatible solutes: The key to Listeria's success as a versatile gastrointestinal pathogen?

Roy D. Sleator
, Colin Hill

Research output: Contribution to journal › Review article › peer-review

Abstract

Recently we reported a role for compatible solute uptake in mediating bile tolerance and increased gastrointestinal persistence in the foodborne pathogen Listeria monocytogenes 1. Herein, we review the evolution in our understanding of how these low molecular weight molecules contribute to growth and survival of the pathogen both inside and outside the body, and how this stress survival mechanism may ultimately be used to target and kill the pathogen.

Original language	English
Article number	20
Journal	Gut Pathogens
Volume	2
Issue number	1
DOIs	https://doi.org/10.1186/1757-4749-2-20
Publication status	Published - 2010

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title = "Compatible solutes: The key to Listeria's success as a versatile gastrointestinal pathogen?",

abstract = "Recently we reported a role for compatible solute uptake in mediating bile tolerance and increased gastrointestinal persistence in the foodborne pathogen Listeria monocytogenes 1. Herein, we review the evolution in our understanding of how these low molecular weight molecules contribute to growth and survival of the pathogen both inside and outside the body, and how this stress survival mechanism may ultimately be used to target and kill the pathogen.",

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AU - Sleator, Roy D.

AU - Hill, Colin

PY - 2010

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N2 - Recently we reported a role for compatible solute uptake in mediating bile tolerance and increased gastrointestinal persistence in the foodborne pathogen Listeria monocytogenes 1. Herein, we review the evolution in our understanding of how these low molecular weight molecules contribute to growth and survival of the pathogen both inside and outside the body, and how this stress survival mechanism may ultimately be used to target and kill the pathogen.

AB - Recently we reported a role for compatible solute uptake in mediating bile tolerance and increased gastrointestinal persistence in the foodborne pathogen Listeria monocytogenes 1. Herein, we review the evolution in our understanding of how these low molecular weight molecules contribute to growth and survival of the pathogen both inside and outside the body, and how this stress survival mechanism may ultimately be used to target and kill the pathogen.

UR - https://www.scopus.com/pages/publications/82055176201

U2 - 10.1186/1757-4749-2-20

DO - 10.1186/1757-4749-2-20

M3 - Review article

AN - SCOPUS:82055176201

SN - 1757-4749

VL - 2

JO - Gut Pathogens

JF - Gut Pathogens

IS - 1

M1 - 20

ER -

Compatible solutes: The key to Listeria's success as a versatile gastrointestinal pathogen?

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