TY - JOUR
T1 - Computed tomography versus radiography for the detection of rib and skull fractures in paediatric suspected physical abuse
T2 - a systematic review
AU - Mohammed, Ahmed
AU - Mahon, Eimear
AU - Moore, Niamh
AU - Sweetman, Lorna
AU - Maher, Michael
AU - O’Regan, Patrick
AU - England, Andrew
AU - McEntee, Mark F.
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.
PY - 2025/1
Y1 - 2025/1
N2 - The diagnosis of suspected physical abuse (SPA) remains a continuous challenge to paediatric healthcare. Several studies have reported that computed tomography (CT) improves the evaluation of SPA. This study aims to systematically review the diagnostic performance of CT compared to radiography in investigating skull and chest fractures for SPA. Multiple databases were searched, using PRISMA methods, from 2008 to August 2024 for relevant studies in English. Two reviewers independently screened and selected relevant studies using Covidence software. The QUADAS-2 tool was used for the quality assessment of the included papers. Sensitivity, specificity and the effective radiation dose of CT and radiography from the included studies were extracted. Pooled sensitivity and specificity were calculated with their respective 95% confidence intervals (CI). GRADE criteria were used to appraise the overall quality of the synthesis. Of the 4057 identified papers, 10 met the inclusion criteria; all 10 included skull and/or chest. The overall sensitivity and specificity of CT were 96.5% (95% CI, 94.9–97.7%) and 99.5% (95% CI, 99.1–99.8%), respectively. Compared to the sensitivity and specificity of radiography, 59.8% (95% CI, 56.2–63.3%) and 99.7% (95% CI, 99.3–99.8%), respectively. Conclusion: CT sensitivity is significantly higher than radiography in detecting rib and skull fractures for SPA. The effective dose for chest LDCT is comparable to that of radiography. Therefore, LDCT should be considered a potential replacement to radiography in SPA investigations for the chest and skull. (Table presented.)
AB - The diagnosis of suspected physical abuse (SPA) remains a continuous challenge to paediatric healthcare. Several studies have reported that computed tomography (CT) improves the evaluation of SPA. This study aims to systematically review the diagnostic performance of CT compared to radiography in investigating skull and chest fractures for SPA. Multiple databases were searched, using PRISMA methods, from 2008 to August 2024 for relevant studies in English. Two reviewers independently screened and selected relevant studies using Covidence software. The QUADAS-2 tool was used for the quality assessment of the included papers. Sensitivity, specificity and the effective radiation dose of CT and radiography from the included studies were extracted. Pooled sensitivity and specificity were calculated with their respective 95% confidence intervals (CI). GRADE criteria were used to appraise the overall quality of the synthesis. Of the 4057 identified papers, 10 met the inclusion criteria; all 10 included skull and/or chest. The overall sensitivity and specificity of CT were 96.5% (95% CI, 94.9–97.7%) and 99.5% (95% CI, 99.1–99.8%), respectively. Compared to the sensitivity and specificity of radiography, 59.8% (95% CI, 56.2–63.3%) and 99.7% (95% CI, 99.3–99.8%), respectively. Conclusion: CT sensitivity is significantly higher than radiography in detecting rib and skull fractures for SPA. The effective dose for chest LDCT is comparable to that of radiography. Therefore, LDCT should be considered a potential replacement to radiography in SPA investigations for the chest and skull. (Table presented.)
KW - Chest
KW - Diagnosis
KW - Head
KW - Non-accidental injury
KW - Skeletal survey
UR - https://www.scopus.com/pages/publications/85211118517
U2 - 10.1007/s00431-024-05894-9
DO - 10.1007/s00431-024-05894-9
M3 - Article
C2 - 39644362
AN - SCOPUS:85211118517
SN - 0340-6199
VL - 184
JO - European Journal of Pediatrics
JF - European Journal of Pediatrics
IS - 1
M1 - 69
ER -