Corrigendum to “Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides” (Journal of Controlled Release (2019) 304 (191–203), (S0168365919302573), (10.1016/j.jconrel.2019.05.009))

The authors regret that the legend for Fig. 5 in the original version of the article contains the following error: The Fig. 5 legend text currently reads; Fig. 5 Star-PLL-pDNA gene activated scaffolds are biocompatible both in vitro and in vivo. Illustrated above is (A) the metabolic activity of MSCs seeded onto a range of gene activated collagen-CS scaffolds including a gene-free control scaffold, PEI-pGLuc (N/P 10, 2μg pGLuc), L-PLL-pGLuc (M:R 2:1, 1μg pGLuc), 32-star-pLL-pGLuc (N/P 5, 2μg pGLuc) and 64-star-PLL-pGLuc (N/P 5, 5μg pGLuc). Data is expressed as a mean percentage metabolic health ± SD (n=3) compared to the untreated control scaffold.(B) Representative H&E stained sections depicting the prompt infiltration of autologous host cells into either a (B) gene-free scaffold, (C) PEI-pGFP (N/P 10, 5 μg pGLuc), (D) 32-star-PLL-pGLuc (N/P 5, 5 μg pGLuc) or (E) 64-star-PLL-pGLuc (N/P 5, 5 μg pGLuc) one-week post implantation into the dorsal subcutaneous tissue of male Wistar rats. Cellular influx is observed from the surrounding tissues through to the centre of each scaffold with black arrows indicating the host/scaffold interface. Images were taken at (i) 10× magnification and (ii) 20× magnification. Scale bar = 100 μm. Whereas it should read; Fig. 5 Star-PLL-pDNA gene activated scaffolds are biocompatible both in vitro and in vivo. Illustrated above is (A) the metabolic activity of MSCs seeded onto a range of gene activated collagen-CS scaffolds including a gene-free control scaffold, PEI-pGLuc (N/P 10, 2μg pGLuc), L-PLL-pGLuc (M:R 2:1, 1μg pGLuc), 32-star-pLL-pGLuc (N/P 5, 2μg pGLuc) and 64-star-PLL-pGLuc (N/P 5, 5μg pGLuc). Data is expressed as a mean percentage metabolic health ± SD (n=3) compared to the untreated control scaffold. Representative H&E stained sections depicting the prompt infiltration of autologous host cells into either a (B) gene-free scaffold, (C) PEI-pGFP (N/P 10, 5 μg pGFP), (D) 32-star-PLL-pGFP (N/P 5, 5 μg pGFP) or (E) 64-star-PLL-pGFP (N/P 5, 5 μg pGFP) one-week post implantation into the dorsal subcutaneous tissue of male Wistar rats. Cellular influx is observed from the surrounding tissues through to the centre of each scaffold with black arrows indicating the host/scaffold interface. Images were taken at (i) 10× magnification and (ii) 20× magnification. Scale bar = 100 μm. The authors apologize for any inconvenience caused.