Abstract
The design of mechanically clutched cranial perforators, used in craniotomy procedures, limits their performance under certain clinical conditions and can, in some cases, impose the risk of severe brain injury on patients undergoing the procedure. An additional safety mechanism could help in mitigating these risks. In this work, we examine the use of diffuse reflectance spectroscopy as a potential fallback mechanism for near real-time detection of the bone-brain boundary. Monte Carlo simulation of a two layer model with optical properties of bone and brain at 530 and 850 nm resulted in a detectable change in diffuse reflectance signal when approaching the boundary. The simulated results were used to guide the development of an experimental drill control system, which was tested on 10 sheep craniums and yielded 88.1% success rate in the detection of the approaching bone-brain boundary.
| Original language | English |
|---|---|
| Article number | 9069487 |
| Pages (from-to) | 3474-3482 |
| Number of pages | 9 |
| Journal | IEEE Transactions on Biomedical Engineering |
| Volume | 67 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 2020 |
Keywords
- cranial perforator
- Diffuse reflectance spectroscopy
- surgical guidance
- tissue boundary detection
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