Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation

Jane A. English; Caitriona Scaife; Akiko Harauma; Melanie Focking; Kieran Wynne; Gerard Cagney; Toru Moriguchi; David R. Cotter

doi:10.1016/j.dib.2015.12.057

Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation

Jane A. English
, Caitriona Scaife
, Akiko Harauma
, Melanie Focking
, Kieran Wynne
, Gerard Cagney
, Toru Moriguchi
, David R. Cotter

Research output: Contribution to journal › Article › peer-review

Abstract

This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.

Original language	English
Pages (from-to)	341-343
Number of pages	3
Journal	Data in Brief
Volume	7
DOIs	https://doi.org/10.1016/j.dib.2015.12.057
Publication status	Published - 1 Jun 2016
Externally published	Yes

Keywords

Brain
Hippocampus
Mass spectrometry
Mouse
Omega-3 deficiency
Proteins
Proteomics

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10.1016/j.dib.2015.12.057

Cite this

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title = "Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation",

abstract = "This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article {"}Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus{"} (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.",

keywords = "Brain, Hippocampus, Mass spectrometry, Mouse, Omega-3 deficiency, Proteins, Proteomics",

author = "English, \{Jane A.\} and Caitriona Scaife and Akiko Harauma and Melanie Focking and Kieran Wynne and Gerard Cagney and Toru Moriguchi and Cotter, \{David R.\}",

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year = "2016",

month = jun,

day = "1",

doi = "10.1016/j.dib.2015.12.057",

language = "English",

volume = "7",

pages = "341--343",

journal = "Data in Brief",

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TY - JOUR

T1 - Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation

AU - English, Jane A.

AU - Scaife, Caitriona

AU - Harauma, Akiko

AU - Focking, Melanie

AU - Wynne, Kieran

AU - Cagney, Gerard

AU - Moriguchi, Toru

AU - Cotter, David R.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.

AB - This dataset reports on the analysis of mouse hippocampus by LC-MS/MS, from mice fed a diet that was either deficient in n-3 FA (n-3 Def) or sufficient in n-3 FA (n-3 Adq). Label free quantitative (LFQ) analysis of the mass spectrometry data identified 1008 quantifiable proteins, 115 of which were found to be differentially expressed between the two dietary groups (n=8 per group). This data article refers to the research article "Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus" (English et al., 2013 [1]), in which a more comprehensive interpretation and analysis of the data is given.

KW - Brain

KW - Hippocampus

KW - Mass spectrometry

KW - Mouse

KW - Omega-3 deficiency

KW - Proteins

KW - Proteomics

UR - https://www.scopus.com/pages/publications/84959343844

U2 - 10.1016/j.dib.2015.12.057

DO - 10.1016/j.dib.2015.12.057

M3 - Article

AN - SCOPUS:84959343844

SN - 2352-3409

VL - 7

SP - 341

EP - 343

JO - Data in Brief

JF - Data in Brief

ER -

Dataset of mouse hippocampus profiled by LC-MS/MS for label-free quantitation

Abstract

Keywords

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