Dynamic kinetic resolution in the baker's yeast mediated reduction of 2-benzenesulfonylcycloalkanones

Anita R. Maguire; Noreen O'Riordan

doi:10.1016/S0040-4039(99)01947-4

Dynamic kinetic resolution in the baker's yeast mediated reduction of 2-benzenesulfonylcycloalkanones

Anita R. Maguire
, Noreen O'Riordan

University College Cork

Research output: Contribution to journal › Article › peer-review

Abstract

2-Benzenesulfonylcyclopentanone 1 and -cyclohexanone 2 undergo efficient dynamic kinetic resolution on treatment with baker's yeast, under a range of conditions including in organic solvents, to form the corresponding cis-2-benzenesulfonylcycloalkanols 5 and 6 in excellent enantiopurity. Reduction of larger ring derivatives is much less efficient.

Original language	English
Pages (from-to)	9285-9288
Number of pages	4
Journal	Tetrahedron Letters
Volume	40
Issue number	52
DOIs	https://doi.org/10.1016/S0040-4039(99)01947-4
Publication status	Published - 24 Dec 1999

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title = "Dynamic kinetic resolution in the baker's yeast mediated reduction of 2-benzenesulfonylcycloalkanones",

abstract = "2-Benzenesulfonylcyclopentanone 1 and -cyclohexanone 2 undergo efficient dynamic kinetic resolution on treatment with baker's yeast, under a range of conditions including in organic solvents, to form the corresponding cis-2-benzenesulfonylcycloalkanols 5 and 6 in excellent enantiopurity. Reduction of larger ring derivatives is much less efficient.",

author = "Maguire, \{Anita R.\} and Noreen O'Riordan",

year = "1999",

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T1 - Dynamic kinetic resolution in the baker's yeast mediated reduction of 2-benzenesulfonylcycloalkanones

AU - Maguire, Anita R.

AU - O'Riordan, Noreen

PY - 1999/12/24

Y1 - 1999/12/24

N2 - 2-Benzenesulfonylcyclopentanone 1 and -cyclohexanone 2 undergo efficient dynamic kinetic resolution on treatment with baker's yeast, under a range of conditions including in organic solvents, to form the corresponding cis-2-benzenesulfonylcycloalkanols 5 and 6 in excellent enantiopurity. Reduction of larger ring derivatives is much less efficient.

AB - 2-Benzenesulfonylcyclopentanone 1 and -cyclohexanone 2 undergo efficient dynamic kinetic resolution on treatment with baker's yeast, under a range of conditions including in organic solvents, to form the corresponding cis-2-benzenesulfonylcycloalkanols 5 and 6 in excellent enantiopurity. Reduction of larger ring derivatives is much less efficient.

UR - https://www.scopus.com/pages/publications/0033601434

U2 - 10.1016/S0040-4039(99)01947-4

DO - 10.1016/S0040-4039(99)01947-4

M3 - Article

AN - SCOPUS:0033601434

SN - 0040-4039

VL - 40

SP - 9285

EP - 9288

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 52

ER -

Dynamic kinetic resolution in the baker's yeast mediated reduction of 2-benzenesulfonylcycloalkanones

Abstract

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