Effects of the intestinal microbiota on behavior and brain biochemistry

Eoin Barrett; Timothy G. Dinan; John F. Cryan; Eamonn M.M. Quigley; Fergus Shanahan; Paul W. O'Toole; Gerald F. Fitzgerald; Catherine Stanton; R. Paul Ross

doi:10.1159/000345749

Effects of the intestinal microbiota on behavior and brain biochemistry

Eoin Barrett
, Timothy G. Dinan
, John F. Cryan
, Eamonn M.M. Quigley
, Fergus Shanahan
, Paul W. O'Toole
, Gerald F. Fitzgerald
, Catherine Stanton
, R. Paul Ross

University College Cork
Teagasc - Irish Agriculture and Food Development Authority

Research output: Chapter in Book/Report/Conference proceedings › Chapter › peer-review

Abstract

Increasing evidence is emerging about the influence of the gut microbiota on the brain-gut axis, which has led to the concept of the brain-gut-enteric microbiota axis. In order to study this signaling mechanism, a number of approaches have been used involving animal models which examine the influence of the microbiota on brain function as discussed below. This review focuses on the influence of the gut microbiota on the gut-brain axis, bioactive metabolite production, and the use of probiotics to modulate metabolism and behavior.

Original language	English
Title of host publication	Probiotic Bacteria and Their Effect on Human Health and Well-Being
Editors	Alfredo Guarino, Eamonn M.M. Quigley, W. Allan Walker
Publisher	S. Karger AG
Pages	56-63
Number of pages	8
Volume	107
ISBN (Electronic)	9783318023251
ISBN (Print)	9783318023244
DOIs	https://doi.org/10.1159/000345749
Publication status	Published - 29 Apr 2013

Publication series

Name	World Review of Nutrition and Dietetics
Volume	107
ISSN (Print)	0084-2230
ISSN (Electronic)	1662-3975

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10.1159/000345749

Cite this

Barrett, E., Dinan, T. G., Cryan, J. F., Quigley, E. M. M., Shanahan, F., O'Toole, P. W., Fitzgerald, G. F., Stanton, C., & Ross, R. P. (2013). Effects of the intestinal microbiota on behavior and brain biochemistry. In A. Guarino, E. M. M. Quigley, & W. A. Walker (Eds.), Probiotic Bacteria and Their Effect on Human Health and Well-Being (Vol. 107, pp. 56-63). (World Review of Nutrition and Dietetics; Vol. 107). S. Karger AG. https://doi.org/10.1159/000345749

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abstract = "Increasing evidence is emerging about the influence of the gut microbiota on the brain-gut axis, which has led to the concept of the brain-gut-enteric microbiota axis. In order to study this signaling mechanism, a number of approaches have been used involving animal models which examine the influence of the microbiota on brain function as discussed below. This review focuses on the influence of the gut microbiota on the gut-brain axis, bioactive metabolite production, and the use of probiotics to modulate metabolism and behavior.",

author = "Eoin Barrett and Dinan, \{Timothy G.\} and Cryan, \{John F.\} and Quigley, \{Eamonn M.M.\} and Fergus Shanahan and O'Toole, \{Paul W.\} and Fitzgerald, \{Gerald F.\} and Catherine Stanton and Ross, \{R. Paul\}",

year = "2013",

month = apr,

day = "29",

doi = "10.1159/000345749",

language = "English",

isbn = "9783318023244",

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series = "World Review of Nutrition and Dietetics",

publisher = "S. Karger AG",

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}

Barrett, E, Dinan, TG, Cryan, JF, Quigley, EMM, Shanahan, F, O'Toole, PW, Fitzgerald, GF, Stanton, C & Ross, RP 2013, Effects of the intestinal microbiota on behavior and brain biochemistry. in A Guarino, EMM Quigley & WA Walker (eds), Probiotic Bacteria and Their Effect on Human Health and Well-Being. vol. 107, World Review of Nutrition and Dietetics, vol. 107, S. Karger AG, pp. 56-63. https://doi.org/10.1159/000345749

Effects of the intestinal microbiota on behavior and brain biochemistry. / Barrett, Eoin; Dinan, Timothy G.; Cryan, John F. et al.
Probiotic Bacteria and Their Effect on Human Health and Well-Being. ed. / Alfredo Guarino; Eamonn M.M. Quigley; W. Allan Walker. Vol. 107 S. Karger AG, 2013. p. 56-63 (World Review of Nutrition and Dietetics; Vol. 107).

Research output: Chapter in Book/Report/Conference proceedings › Chapter › peer-review

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T1 - Effects of the intestinal microbiota on behavior and brain biochemistry

AU - Barrett, Eoin

AU - Dinan, Timothy G.

AU - Cryan, John F.

AU - Quigley, Eamonn M.M.

AU - Shanahan, Fergus

AU - O'Toole, Paul W.

AU - Fitzgerald, Gerald F.

AU - Stanton, Catherine

AU - Ross, R. Paul

PY - 2013/4/29

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N2 - Increasing evidence is emerging about the influence of the gut microbiota on the brain-gut axis, which has led to the concept of the brain-gut-enteric microbiota axis. In order to study this signaling mechanism, a number of approaches have been used involving animal models which examine the influence of the microbiota on brain function as discussed below. This review focuses on the influence of the gut microbiota on the gut-brain axis, bioactive metabolite production, and the use of probiotics to modulate metabolism and behavior.

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A2 - Guarino, Alfredo

A2 - Quigley, Eamonn M.M.

A2 - Walker, W. Allan

PB - S. Karger AG

ER -

Effects of the intestinal microbiota on behavior and brain biochemistry

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