TY - JOUR
T1 - Efficient kinetic resolution of 2-benzenesulfonylcyclopentanone derivatives [J. Mol. Catal., 1 (1996) 115-126]
AU - Maguire, Anita R.
AU - Kelleher, Leonard L.
AU - Ferguson, George
PY - 1996
Y1 - 1996
N2 - Efficient kinetic resolution of 2-benzenesulfonylcyclopentanones 1, bearing 3-alkyl, 3-aryl, or 3-benzyl substituents, has been achieved by bakers' yeast mediated reduction. With the unsubstituted 2-benzenesulfonylcyclopentanone 1a, efficient asymmetric reduction to form (1S,2R)-cis-2-benzenesulfonylcyclopentanol 2a is observed under the same conditions. Excellent enantioselectivities (up to >95% ee) are obtained.
AB - Efficient kinetic resolution of 2-benzenesulfonylcyclopentanones 1, bearing 3-alkyl, 3-aryl, or 3-benzyl substituents, has been achieved by bakers' yeast mediated reduction. With the unsubstituted 2-benzenesulfonylcyclopentanone 1a, efficient asymmetric reduction to form (1S,2R)-cis-2-benzenesulfonylcyclopentanol 2a is observed under the same conditions. Excellent enantioselectivities (up to >95% ee) are obtained.
UR - https://www.scopus.com/pages/publications/0030569501
U2 - 10.1016/S1381-1177(96)00026-4
DO - 10.1016/S1381-1177(96)00026-4
M3 - Comment/Debate
AN - SCOPUS:0030569501
SN - 1381-1177
VL - 2
SP - 147
EP - 158
JO - Journal of Molecular Catalysis - B Enzymatic
JF - Journal of Molecular Catalysis - B Enzymatic
IS - 2-3
ER -