Evaluation of carboplatin dosage based on 4-variable modification of diet in renal disease equation

A. Barry; R. O'Cearbhaill; D. Griffin; P. Donnellan; M. Keane; H. Grimes

doi:10.1007/s11845-008-0250-z

Evaluation of carboplatin dosage based on 4-variable modification of diet in renal disease equation

A. Barry
, R. O'Cearbhaill
, D. Griffin
, P. Donnellan
, M. Keane
, H. Grimes

Research output: Contribution to journal › Article › peer-review

Abstract

Background Traditionally, carboplatin dosage is based on the Calvert formula. Glomerular filtration rate (GFR) and creatinine clearance (CrCl) are often used interchangeably in this formula. The modification of diet in renal disease (MDRD) equation is now routinely available to estimate GFR (eGFR). Methods We performed a retrospective analysis of carboplatin dosage in our institute. Calvert formula derived carboplatin dose using eGFR calculated from the MDRD equation was compared to estimated CrCl from the Cockcroft- Gault and Jelliffe equations.

Original language	English
Pages (from-to)	301-307
Number of pages	7
Journal	Irish Journal of Medical Science
Volume	178
Issue number	3
DOIs	https://doi.org/10.1007/s11845-008-0250-z
Publication status	Published - Sep 2009
Externally published	Yes

Keywords

Calvert formula
Carboplatin
Creatinine clearance
Estimated glomerular filtration rate
Modification of diet in renal disease

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10.1007/s11845-008-0250-z

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title = "Evaluation of carboplatin dosage based on 4-variable modification of diet in renal disease equation",

abstract = "Background Traditionally, carboplatin dosage is based on the Calvert formula. Glomerular filtration rate (GFR) and creatinine clearance (CrCl) are often used interchangeably in this formula. The modification of diet in renal disease (MDRD) equation is now routinely available to estimate GFR (eGFR). Methods We performed a retrospective analysis of carboplatin dosage in our institute. Calvert formula derived carboplatin dose using eGFR calculated from the MDRD equation was compared to estimated CrCl from the Cockcroft- Gault and Jelliffe equations.",

keywords = "Calvert formula, Carboplatin, Creatinine clearance, Estimated glomerular filtration rate, Modification of diet in renal disease",

author = "A. Barry and R. O'Cearbhaill and D. Griffin and P. Donnellan and M. Keane and H. Grimes",

year = "2009",

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doi = "10.1007/s11845-008-0250-z",

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TY - JOUR

T1 - Evaluation of carboplatin dosage based on 4-variable modification of diet in renal disease equation

AU - Barry, A.

AU - O'Cearbhaill, R.

AU - Griffin, D.

AU - Donnellan, P.

AU - Keane, M.

AU - Grimes, H.

PY - 2009/9

Y1 - 2009/9

N2 - Background Traditionally, carboplatin dosage is based on the Calvert formula. Glomerular filtration rate (GFR) and creatinine clearance (CrCl) are often used interchangeably in this formula. The modification of diet in renal disease (MDRD) equation is now routinely available to estimate GFR (eGFR). Methods We performed a retrospective analysis of carboplatin dosage in our institute. Calvert formula derived carboplatin dose using eGFR calculated from the MDRD equation was compared to estimated CrCl from the Cockcroft- Gault and Jelliffe equations.

AB - Background Traditionally, carboplatin dosage is based on the Calvert formula. Glomerular filtration rate (GFR) and creatinine clearance (CrCl) are often used interchangeably in this formula. The modification of diet in renal disease (MDRD) equation is now routinely available to estimate GFR (eGFR). Methods We performed a retrospective analysis of carboplatin dosage in our institute. Calvert formula derived carboplatin dose using eGFR calculated from the MDRD equation was compared to estimated CrCl from the Cockcroft- Gault and Jelliffe equations.

KW - Calvert formula

KW - Carboplatin

KW - Creatinine clearance

KW - Estimated glomerular filtration rate

KW - Modification of diet in renal disease

UR - https://www.scopus.com/pages/publications/70449697970

U2 - 10.1007/s11845-008-0250-z

DO - 10.1007/s11845-008-0250-z

M3 - Article

C2 - 19002550

AN - SCOPUS:70449697970

SN - 0021-1265

VL - 178

SP - 301

EP - 307

JO - Irish Journal of Medical Science

JF - Irish Journal of Medical Science

IS - 3

ER -

Evaluation of carboplatin dosage based on 4-variable modification of diet in renal disease equation

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Keywords

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