TY - JOUR
T1 - Festschrift for Ronan O’Connell
T2 - pouchitis, ulcerative colitis and the microbiome
AU - Lavelle, Aonghus
N1 - Publisher Copyright:
© 2018, Royal Academy of Medicine in Ireland.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - The hypothesis of altered bacterial communities contributing to the development of pouchitis began a scientific quest to link host mucosal factors, microbial metabolism and spatial structure of the colonic microbiome in ulcerative colitis, reaching its apotheosis with the integration of advanced spatial sampling with laser capture microdissection, mucin array profiling, molecular microbiology and next-generation sequencing technologies. This article, part of a festschrift, summarises the contributions of the O’Connell lab to the field of host-microbial interactions in inflammatory bowel disease.
AB - The hypothesis of altered bacterial communities contributing to the development of pouchitis began a scientific quest to link host mucosal factors, microbial metabolism and spatial structure of the colonic microbiome in ulcerative colitis, reaching its apotheosis with the integration of advanced spatial sampling with laser capture microdissection, mucin array profiling, molecular microbiology and next-generation sequencing technologies. This article, part of a festschrift, summarises the contributions of the O’Connell lab to the field of host-microbial interactions in inflammatory bowel disease.
KW - Inflammatory bowel disease
KW - Microbiome
KW - Pouchitis
UR - https://www.scopus.com/pages/publications/85043378210
U2 - 10.1007/s11845-018-1785-2
DO - 10.1007/s11845-018-1785-2
M3 - Review article
C2 - 29524104
AN - SCOPUS:85043378210
SN - 0021-1265
VL - 187
SP - 1133
EP - 1137
JO - Irish Journal of Medical Science
JF - Irish Journal of Medical Science
IS - 4
ER -