From offline to online kidney exchange optimization

Kidney exchange programs enable willing, but incompatible, donor-patient pairs to swap donors, thus allowing persons suffering from organ failure to access transplantation. Choosing which pairs to match requires solving a stochastic online optimization problem where patients and donors arrive over time. Despite this, most of the related scientific literature has focused on deterministic offline models. In this paper, we present a simple approach to employ a model for the offline Kidney Exchange Problem (KEP) as the basis of an on-line anticipatory algorithm. Our approach grounds on existing techniques for the on-line KEP, but it generalizes them and provides a more accurate estimate of the expected impact of current decisions. In an experimentation based on a state-of-the-art donor pool generation method, the approach provides improvements in terms of quality and is able to deal with realistic instance size in reasonable time.