Functioning acinar cell pancreatic carcinoma: Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

Dushyant Sahani; Srinivasa R. Prasad; Michael Maher; Andrew L. Warshaw; Peter F. Hahn; Sanjay Saini

doi:10.1097/00004728-200201000-00019

Functioning acinar cell pancreatic carcinoma: Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

Dushyant Sahani
, Srinivasa R. Prasad
, Michael Maher
, Andrew L. Warshaw
, Peter F. Hahn
, Sanjay Saini

Harvard University

Research output: Contribution to journal › Article › peer-review

Abstract

We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.

Original language	English
Pages (from-to)	126-128
Number of pages	3
Journal	Journal of Computer Assisted Tomography
Volume	26
Issue number	1
DOIs	https://doi.org/10.1097/00004728-200201000-00019
Publication status	Published - 2002
Externally published	Yes

Keywords

Acinar cell - Magnetic resonance imaging
Carcinoma
Pancreas

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10.1097/00004728-200201000-00019

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abstract = "We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.",

keywords = "Acinar cell - Magnetic resonance imaging, Carcinoma, Pancreas",

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doi = "10.1097/00004728-200201000-00019",

language = "English",

volume = "26",

pages = "126--128",

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T2 - Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

AU - Sahani, Dushyant

AU - Prasad, Srinivasa R.

AU - Maher, Michael

AU - Warshaw, Andrew L.

AU - Hahn, Peter F.

AU - Saini, Sanjay

PY - 2002

Y1 - 2002

N2 - We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.

AB - We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.

KW - Acinar cell - Magnetic resonance imaging

KW - Carcinoma

KW - Pancreas

UR - https://www.scopus.com/pages/publications/0036145849

U2 - 10.1097/00004728-200201000-00019

DO - 10.1097/00004728-200201000-00019

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AN - SCOPUS:0036145849

SN - 0363-8715

VL - 26

SP - 126

EP - 128

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

IS - 1

ER -

Functioning acinar cell pancreatic carcinoma: Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

Abstract

Keywords

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