Further intracellular proteins and signaling pathways regulated by angiotensin-(1–7) in human endothelial cells

Christian Meinert; Franziska Kohse; Ilka Böhme; Florian Gembardt; Anja Tetzner; Thomas Wieland; Barry Greenberg; Thomas Walther

doi:10.1016/j.dib.2016.12.004

Further intracellular proteins and signaling pathways regulated by angiotensin-(1–7) in human endothelial cells

Christian Meinert
, Franziska Kohse
, Ilka Böhme
, Florian Gembardt
, Anja Tetzner
, Thomas Wieland
, Barry Greenberg
, Thomas Walther

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

In 2016, Meinert et al. (doi: 10.1016/j.jprot.2015.09.020) published the first 25 proteins in a protein array regulated in Human Umbilical Vein Endothelial Cells (HUVEC) by the heptapeptide angiotensin (Ang)-(1–7) and the first 10 intracellular signaling cascades at different time points. This supporting data article shows further proteins and pathways stimulated by Ang-(1–7) in human endothelial cells at time points of 1 h, 3 h, 6 h, and 9 h. HUVECs were stimulated with Ang-(1–7), and regulated proteins were identified via antibody microarray. Bioinformatics software IPA was used for association of regulated proteins to metabolic pathways.

Original language	English
Pages (from-to)	354-363
Number of pages	10
Journal	Data in Brief
Volume	10
DOIs	https://doi.org/10.1016/j.dib.2016.12.004
Publication status	Published - 1 Feb 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Angiotensin-(1-7)
Antibody microarray
Cell signaling
Endothelium
Renin-Angiotensin system

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10.1016/j.dib.2016.12.004

Cite this

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title = "Further intracellular proteins and signaling pathways regulated by angiotensin-(1–7) in human endothelial cells",

abstract = "In 2016, Meinert et al. (doi: 10.1016/j.jprot.2015.09.020) published the first 25 proteins in a protein array regulated in Human Umbilical Vein Endothelial Cells (HUVEC) by the heptapeptide angiotensin (Ang)-(1–7) and the first 10 intracellular signaling cascades at different time points. This supporting data article shows further proteins and pathways stimulated by Ang-(1–7) in human endothelial cells at time points of 1 h, 3 h, 6 h, and 9 h. HUVECs were stimulated with Ang-(1–7), and regulated proteins were identified via antibody microarray. Bioinformatics software IPA was used for association of regulated proteins to metabolic pathways.",

keywords = "Angiotensin-(1-7), Antibody microarray, Cell signaling, Endothelium, Renin-Angiotensin system",

author = "Christian Meinert and Franziska Kohse and Ilka B{\"o}hme and Florian Gembardt and Anja Tetzner and Thomas Wieland and Barry Greenberg and Thomas Walther",

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year = "2017",

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doi = "10.1016/j.dib.2016.12.004",

language = "English",

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TY - JOUR

T1 - Further intracellular proteins and signaling pathways regulated by angiotensin-(1–7) in human endothelial cells

AU - Meinert, Christian

AU - Kohse, Franziska

AU - Böhme, Ilka

AU - Gembardt, Florian

AU - Tetzner, Anja

AU - Wieland, Thomas

AU - Greenberg, Barry

AU - Walther, Thomas

PY - 2017/2/1

Y1 - 2017/2/1

N2 - In 2016, Meinert et al. (doi: 10.1016/j.jprot.2015.09.020) published the first 25 proteins in a protein array regulated in Human Umbilical Vein Endothelial Cells (HUVEC) by the heptapeptide angiotensin (Ang)-(1–7) and the first 10 intracellular signaling cascades at different time points. This supporting data article shows further proteins and pathways stimulated by Ang-(1–7) in human endothelial cells at time points of 1 h, 3 h, 6 h, and 9 h. HUVECs were stimulated with Ang-(1–7), and regulated proteins were identified via antibody microarray. Bioinformatics software IPA was used for association of regulated proteins to metabolic pathways.

AB - In 2016, Meinert et al. (doi: 10.1016/j.jprot.2015.09.020) published the first 25 proteins in a protein array regulated in Human Umbilical Vein Endothelial Cells (HUVEC) by the heptapeptide angiotensin (Ang)-(1–7) and the first 10 intracellular signaling cascades at different time points. This supporting data article shows further proteins and pathways stimulated by Ang-(1–7) in human endothelial cells at time points of 1 h, 3 h, 6 h, and 9 h. HUVECs were stimulated with Ang-(1–7), and regulated proteins were identified via antibody microarray. Bioinformatics software IPA was used for association of regulated proteins to metabolic pathways.

KW - Angiotensin-(1-7)

KW - Antibody microarray

KW - Cell signaling

KW - Endothelium

KW - Renin-Angiotensin system

UR - https://www.scopus.com/pages/publications/85017308138

U2 - 10.1016/j.dib.2016.12.004

DO - 10.1016/j.dib.2016.12.004

M3 - Article

AN - SCOPUS:85017308138

SN - 2352-3409

VL - 10

SP - 354

EP - 363

JO - Data in Brief

JF - Data in Brief

ER -

Further intracellular proteins and signaling pathways regulated by angiotensin-(1–7) in human endothelial cells

Abstract

UN SDGs

Keywords

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