Gating and intrafraction drift correction on a 1.5 T MR-Linac: Clinical dosimetric benefits for upper abdominal tumors

Guus Grimbergen; Sara L Hackett; Fasco van Ommen; Astrid L H M W van Lier; Pim T S Borman; Lieke T C Meijers; Eline N de Groot-van Breugel; Johannes C J de Boer; Bas W Raaymakers; Martijn P W Intven; Gert J Meijer

doi:10.1016/j.radonc.2023.109932

Gating and intrafraction drift correction on a 1.5 T MR-Linac: Clinical dosimetric benefits for upper abdominal tumors

Guus Grimbergen
, Sara L Hackett
, Fasco van Ommen
, Astrid L H M W van Lier
, Pim T S Borman
, Lieke T C Meijers
, Eline N de Groot-van Breugel
, Johannes C J de Boer
, Bas W Raaymakers
, Martijn P W Intven
, Gert J Meijer

School of Medicine

University Medical Centre Utrecht

Research output: Contribution to journal › Article › peer-review

Abstract

This work reports on the first seven patients treated with gating and baseline drift correction on the high-field MR-Linac system. Dosimetric analysis showed that the active motion management system improved congruence to the planned dose, efficiently mitigating detrimental effects of intrafraction motion in the upper abdomen.

Original language	English
Pages (from-to)	109932
Journal	Radiotherapy and Oncology
Volume	189
DOIs	https://doi.org/10.1016/j.radonc.2023.109932
Publication status	Published - Dec 2023

Keywords

Humans
Radiotherapy, Intensity-Modulated
Movement
Motion
Radiometry
Abdominal Neoplasms/radiotherapy
Radiotherapy Planning, Computer-Assisted

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10.1016/j.radonc.2023.109932

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Grimbergen, G., Hackett, S. L., van Ommen, F., van Lier, A. L. H. M. W., Borman, P. T. S., Meijers, L. T. C., de Groot-van Breugel, E. N., de Boer, J. C. J., Raaymakers, B. W., Intven, M. P. W., & Meijer, G. J. (2023). Gating and intrafraction drift correction on a 1.5 T MR-Linac: Clinical dosimetric benefits for upper abdominal tumors. Radiotherapy and Oncology, 189, 109932. https://doi.org/10.1016/j.radonc.2023.109932

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title = "Gating and intrafraction drift correction on a 1.5 T MR-Linac: Clinical dosimetric benefits for upper abdominal tumors",

abstract = "This work reports on the first seven patients treated with gating and baseline drift correction on the high-field MR-Linac system. Dosimetric analysis showed that the active motion management system improved congruence to the planned dose, efficiently mitigating detrimental effects of intrafraction motion in the upper abdomen.",

keywords = "Humans, Radiotherapy, Intensity-Modulated, Movement, Motion, Radiometry, Abdominal Neoplasms/radiotherapy, Radiotherapy Planning, Computer-Assisted",

author = "Guus Grimbergen and Hackett, \{Sara L\} and \{van Ommen\}, Fasco and \{van Lier\}, \{Astrid L H M W\} and Borman, \{Pim T S\} and Meijers, \{Lieke T C\} and \{de Groot-van Breugel\}, \{Eline N\} and \{de Boer\}, \{Johannes C J\} and Raaymakers, \{Bas W\} and Intven, \{Martijn P W\} and Meijer, \{Gert J\}",

year = "2023",

month = dec,

doi = "10.1016/j.radonc.2023.109932",

language = "English",

volume = "189",

pages = "109932",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

publisher = "Elsevier Ireland Ltd",

}

Grimbergen, G, Hackett, SL, van Ommen, F, van Lier, ALHMW, Borman, PTS, Meijers, LTC, de Groot-van Breugel, EN, de Boer, JCJ, Raaymakers, BW, Intven, MPW & Meijer, GJ 2023, 'Gating and intrafraction drift correction on a 1.5 T MR-Linac: Clinical dosimetric benefits for upper abdominal tumors', Radiotherapy and Oncology, vol. 189, pp. 109932. https://doi.org/10.1016/j.radonc.2023.109932

TY - JOUR

T1 - Gating and intrafraction drift correction on a 1.5 T MR-Linac

T2 - Clinical dosimetric benefits for upper abdominal tumors

AU - Grimbergen, Guus

AU - Hackett, Sara L

AU - van Ommen, Fasco

AU - van Lier, Astrid L H M W

AU - Borman, Pim T S

AU - Meijers, Lieke T C

AU - de Groot-van Breugel, Eline N

AU - de Boer, Johannes C J

AU - Raaymakers, Bas W

AU - Intven, Martijn P W

AU - Meijer, Gert J

PY - 2023/12

Y1 - 2023/12

N2 - This work reports on the first seven patients treated with gating and baseline drift correction on the high-field MR-Linac system. Dosimetric analysis showed that the active motion management system improved congruence to the planned dose, efficiently mitigating detrimental effects of intrafraction motion in the upper abdomen.

AB - This work reports on the first seven patients treated with gating and baseline drift correction on the high-field MR-Linac system. Dosimetric analysis showed that the active motion management system improved congruence to the planned dose, efficiently mitigating detrimental effects of intrafraction motion in the upper abdomen.

KW - Humans

KW - Radiotherapy, Intensity-Modulated

KW - Movement

KW - Motion

KW - Radiometry

KW - Abdominal Neoplasms/radiotherapy

KW - Radiotherapy Planning, Computer-Assisted

UR - http://europepmc.org/abstract/med/37778533

U2 - 10.1016/j.radonc.2023.109932

DO - 10.1016/j.radonc.2023.109932

M3 - Article

C2 - 37778533

SN - 0167-8140

VL - 189

SP - 109932

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

ER -

Gating and intrafraction drift correction on a 1.5 T MR-Linac: Clinical dosimetric benefits for upper abdominal tumors

Abstract

Keywords

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