Skip to main navigation Skip to search Skip to main content

Gene expression data visualization tool on the o²S²PARC platform

  • Hiba Ben Aribi
  • , Mengyuan Ding
  • , Anmol Kiran

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The identification of differentially expressed genes and their associated biological processes, molecular function, and cellular components are essential for genetic disease studies because they present potential biomarkers and therapeutic targets. Methods: In this study, we developed an o²S²PARC template to instantiate an interactive pipeline for gene expression data visualization, ontological mapping, and statistical evaluation. To demonstrate the tool's usefulness, we performed a case study on a publicly available dataset. Results: The tool enables users to identify the differentially expressed genes (DEGs) and visualize them in a volcano plot format. Ontologies associated with the DEGs are assigned and visualized in barplots. Conclusions: The “Expression data visualization” template is publicly available on the o²S²PARC platform.

Original languageEnglish
Article number1267
JournalF1000Research
Volume11
DOIs
Publication statusPublished - 2023
Externally publishedYes

Keywords

  • Gene expression
  • Ontology
  • o²S²PARC
  • Visualization

Fingerprint

Dive into the research topics of 'Gene expression data visualization tool on the o²S²PARC platform'. Together they form a unique fingerprint.

Cite this