TY - JOUR
T1 - Generation of induced pluripotent stem cells from two ADHD patients and two healthy controls
AU - Yde Ohki, Cristine Marie
AU - Walter, Natalie Monet
AU - Rickli, Michelle
AU - Van Puyenbroeck, Pakita
AU - Döring, Christian
AU - Hoffmann, Per
AU - Herms, Stefan
AU - Maria Werling, Anna
AU - Walitza, Susanne
AU - Grünblatt, Edna
N1 - Publisher Copyright:
© 2023 The Author(s)
PY - 2023/6
Y1 - 2023/6
N2 - Attention-deficit hyperactivity disorder is a neurodevelopmental disorder which prevalence has been increasing in the past decades, affecting more than 5% of children, adolescents worldwide. Regarding etiology, polygenic, environmental factors contribute to the occurrence of ADHD even though molecular mechanisms are not known. Understanding the pathophysiology in patient-specific cells is crucial for the discovery of potential predictive markers, the establishment of new therapeutic targets. In this study, we generated further lines from ADHD patients, healthy controls using Sendai virus transduction, which may help on the study of ADHD at the molecular, cellular levels.
AB - Attention-deficit hyperactivity disorder is a neurodevelopmental disorder which prevalence has been increasing in the past decades, affecting more than 5% of children, adolescents worldwide. Regarding etiology, polygenic, environmental factors contribute to the occurrence of ADHD even though molecular mechanisms are not known. Understanding the pathophysiology in patient-specific cells is crucial for the discovery of potential predictive markers, the establishment of new therapeutic targets. In this study, we generated further lines from ADHD patients, healthy controls using Sendai virus transduction, which may help on the study of ADHD at the molecular, cellular levels.
UR - https://www.scopus.com/pages/publications/85151279972
U2 - 10.1016/j.scr.2023.103084
DO - 10.1016/j.scr.2023.103084
M3 - Article
C2 - 37004448
AN - SCOPUS:85151279972
SN - 1873-5061
VL - 69
JO - Stem Cell Research
JF - Stem Cell Research
M1 - 103084
ER -