Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients

Leoni Grossmann; Cristine Marie Yde Ohki; Christian Döring; Per Hoffmann; Stefan Herms; Anna Maria Werling; Susanne Walitza; Edna Grünblatt

doi:10.1016/j.scr.2021.102268

Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients

Leoni Grossmann
, Cristine Marie Yde Ohki
, Christian Döring
, Per Hoffmann
, Stefan Herms
, Anna Maria Werling
, Susanne Walitza
, Edna Grünblatt

Research output: Contribution to journal › Article › peer-review

Abstract

Human induced pluripotent stem cell (iPSC) lines have been derived from four male patients with childhood attention-deficit hyperactivity disorder (ADHD). Children and adolescents between the ages 6 and 18 suffering from ADHD were recruited for this work. Isolated keratinocytes or peripheral blood mononuclear cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and c-Myc.

Original language	English
Article number	102268
Journal	Stem Cell Research
Volume	53
DOIs	https://doi.org/10.1016/j.scr.2021.102268
Publication status	Published - May 2021
Externally published	Yes

Access to Document

10.1016/j.scr.2021.102268

Cite this

@article{5beca536c9a4470e9eb88626361fa03a,

title = "Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients",

abstract = "Human induced pluripotent stem cell (iPSC) lines have been derived from four male patients with childhood attention-deficit hyperactivity disorder (ADHD). Children and adolescents between the ages 6 and 18 suffering from ADHD were recruited for this work. Isolated keratinocytes or peripheral blood mononuclear cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and c-Myc.",

author = "Leoni Grossmann and \{Yde Ohki\}, \{Cristine Marie\} and Christian D{\"o}ring and Per Hoffmann and Stefan Herms and Werling, \{Anna Maria\} and Susanne Walitza and Edna Gr{\"u}nblatt",

note = "Publisher Copyright: {\textcopyright} 2021 The Author(s)",

year = "2021",

month = may,

doi = "10.1016/j.scr.2021.102268",

language = "English",

volume = "53",

journal = "Stem Cell Research",

issn = "1873-5061",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients

AU - Grossmann, Leoni

AU - Yde Ohki, Cristine Marie

AU - Döring, Christian

AU - Hoffmann, Per

AU - Herms, Stefan

AU - Werling, Anna Maria

AU - Walitza, Susanne

AU - Grünblatt, Edna

PY - 2021/5

Y1 - 2021/5

N2 - Human induced pluripotent stem cell (iPSC) lines have been derived from four male patients with childhood attention-deficit hyperactivity disorder (ADHD). Children and adolescents between the ages 6 and 18 suffering from ADHD were recruited for this work. Isolated keratinocytes or peripheral blood mononuclear cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and c-Myc.

AB - Human induced pluripotent stem cell (iPSC) lines have been derived from four male patients with childhood attention-deficit hyperactivity disorder (ADHD). Children and adolescents between the ages 6 and 18 suffering from ADHD were recruited for this work. Isolated keratinocytes or peripheral blood mononuclear cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and c-Myc.

UR - https://www.scopus.com/pages/publications/85101669053

U2 - 10.1016/j.scr.2021.102268

DO - 10.1016/j.scr.2021.102268

M3 - Article

C2 - 33662736

AN - SCOPUS:85101669053

SN - 1873-5061

VL - 53

JO - Stem Cell Research

JF - Stem Cell Research

M1 - 102268

ER -

Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients

Abstract

Access to Document

Other files and links

Fingerprint

Cite this