Generation of integration-free induced pluripotent stem cells from healthy individuals

Cristine Marie Yde Ohki; Leoni Grossmann; Christian Döring; Per Hoffmann; Stefan Herms; Anna Maria Werling; Susanne Walitza; Edna Grünblatt

doi:10.1016/j.scr.2021.102269

Generation of integration-free induced pluripotent stem cells from healthy individuals

Cristine Marie Yde Ohki
, Leoni Grossmann
, Christian Döring
, Per Hoffmann
, Stefan Herms
, Anna Maria Werling
, Susanne Walitza
, Edna Grünblatt

Research output: Contribution to journal › Article › peer-review

Abstract

Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6–18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc.

Original language	English
Article number	102269
Journal	Stem Cell Research
Volume	53
DOIs	https://doi.org/10.1016/j.scr.2021.102269
Publication status	Published - May 2021
Externally published	Yes

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title = "Generation of integration-free induced pluripotent stem cells from healthy individuals",

abstract = "Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6–18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc.",

author = "\{Yde Ohki\}, \{Cristine Marie\} and Leoni Grossmann and Christian D{\"o}ring and Per Hoffmann and Stefan Herms and Werling, \{Anna Maria\} and Susanne Walitza and Edna Gr{\"u}nblatt",

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T1 - Generation of integration-free induced pluripotent stem cells from healthy individuals

AU - Yde Ohki, Cristine Marie

AU - Grossmann, Leoni

AU - Döring, Christian

AU - Hoffmann, Per

AU - Herms, Stefan

AU - Werling, Anna Maria

AU - Walitza, Susanne

AU - Grünblatt, Edna

PY - 2021/5

Y1 - 2021/5

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AB - Ten human induced pluripotent stem cell (iPSC) lines have been derived from five healthy controls matched to a study including Attention-Deficit Hyperactivity Disorder patients (ADHD). Both female and male children and adolescents aged 6–18 years were recruited. Isolated keratinocyte cells from the participants were reprogrammed into iPSCs using non-integrating Sendai virus to deliver the reprogramming factors Oct3/4, Sox2, Klf4 and cMyc.

UR - https://www.scopus.com/pages/publications/85101684328

U2 - 10.1016/j.scr.2021.102269

DO - 10.1016/j.scr.2021.102269

M3 - Article

C2 - 33667761

AN - SCOPUS:85101684328

SN - 1873-5061

VL - 53

JO - Stem Cell Research

JF - Stem Cell Research

M1 - 102269

ER -

Generation of integration-free induced pluripotent stem cells from healthy individuals

Abstract

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