TY - JOUR
T1 - Gestational diabetes
T2 - opportunities for improving maternal and child health
AU - Maternal Medicine Clinical Study Group
AU - Royal College of Obstetricians and Gynaecologists, UK
AU - Saravanan, Ponnusamy
AU - Magee, Laura A.
AU - Banerjee, Anita
AU - Coleman, Matthew Anthony
AU - Von Dadelszen, Peter
AU - Denison, Fiona
AU - Farmer, Andrew
AU - Finer, Sarah
AU - Fox-Rushby, Julia
AU - Holt, Richard
AU - Lindsay, Robert S.
AU - MacKillop, Lucy
AU - Maresh, Michael
AU - McAuliffe, Fionnuala M.
AU - McCance, David
AU - McCarthy, Fergus P.
AU - Meek, Claire L.
AU - Murphy, Helen R.
AU - Myers, Jenny
AU - Pasupathy, Dharmintra
AU - Poston, Lucilla
AU - Reynolds, Rebecca M.
AU - Scott, Eleanor
AU - Sukumar, Nithya
AU - Tan, Bee K.
AU - Thangaratinam, Shakila
AU - Webster, Louise
AU - White, Sara Loiuse
AU - Williamson, Catherine
N1 - Publisher Copyright:
© 2020 Elsevier Ltd
PY - 2020/9
Y1 - 2020/9
N2 - Gestational diabetes, the most common medical disorder in pregnancy, is defined as glucose intolerance resulting in hyperglycaemia that begins or is first diagnosed in pregnancy. Gestational diabetes is associated with increased pregnancy complications and long-term metabolic risks for the woman and the offspring. However, the current diagnostic and management strategies recommended by national and international guidelines are mainly focused on short-term risks during pregnancy and delivery, except the Carpenter-Coustan criteria, which were based on the risk of future incidence of type 2 diabetes post-gestational diabetes. In this Personal View, first, we summarise the evidence for long-term risk in women with gestational diabetes and their offspring. Second, we suggest that a shift is needed in the thinking about gestational diabetes; moving from the perception of a short-term condition that confers increased risks of large babies to a potentially modifiable long-term condition that contributes to the growing burden of childhood obesity and cardiometabolic disorders in women and the future generation. Third, we propose how the current clinical practice might be improved. Finally, we outline and justify priorities for future research.
AB - Gestational diabetes, the most common medical disorder in pregnancy, is defined as glucose intolerance resulting in hyperglycaemia that begins or is first diagnosed in pregnancy. Gestational diabetes is associated with increased pregnancy complications and long-term metabolic risks for the woman and the offspring. However, the current diagnostic and management strategies recommended by national and international guidelines are mainly focused on short-term risks during pregnancy and delivery, except the Carpenter-Coustan criteria, which were based on the risk of future incidence of type 2 diabetes post-gestational diabetes. In this Personal View, first, we summarise the evidence for long-term risk in women with gestational diabetes and their offspring. Second, we suggest that a shift is needed in the thinking about gestational diabetes; moving from the perception of a short-term condition that confers increased risks of large babies to a potentially modifiable long-term condition that contributes to the growing burden of childhood obesity and cardiometabolic disorders in women and the future generation. Third, we propose how the current clinical practice might be improved. Finally, we outline and justify priorities for future research.
UR - https://www.scopus.com/pages/publications/85089542145
U2 - 10.1016/S2213-8587(20)30161-3
DO - 10.1016/S2213-8587(20)30161-3
M3 - Review article
C2 - 32822601
AN - SCOPUS:85089542145
SN - 2213-8587
VL - 8
SP - 793
EP - 800
JO - The Lancet Diabetes and Endocrinology
JF - The Lancet Diabetes and Endocrinology
IS - 9
ER -