Host-microbe interactions and spatial variation of cancer in the gut

Fergus Shanahan; Paul W. O'Toole

doi:10.1038/nrc3765

Host-microbe interactions and spatial variation of cancer in the gut

Fergus Shanahan
, Paul W. O'Toole

University College Cork

Research output: Contribution to journal › Review article › peer-review

Abstract

The small intestine has a greater cell mass than the colon, it is longer and with greater surface area and has a faster rate of epithelial turnover. At first, this might suggest that the small bowel epithelium could be at greater risk of the cumulative genetic errors that predispose to cancer. However, the incidence of cancer of the small bowel is more than tenfold lower than that of colorectal cancer.

Original language	English
Pages (from-to)	511-512
Number of pages	2
Journal	Nature Reviews Cancer
Volume	14
Issue number	8
DOIs	https://doi.org/10.1038/nrc3765
Publication status	Published - Aug 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1038/nrc3765

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abstract = "The small intestine has a greater cell mass than the colon, it is longer and with greater surface area and has a faster rate of epithelial turnover. At first, this might suggest that the small bowel epithelium could be at greater risk of the cumulative genetic errors that predispose to cancer. However, the incidence of cancer of the small bowel is more than tenfold lower than that of colorectal cancer.",

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U2 - 10.1038/nrc3765

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M3 - Review article

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JO - Nature Reviews Cancer

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ER -

Host-microbe interactions and spatial variation of cancer in the gut

Abstract

UN SDGs

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