TY - JOUR
T1 - Human Microbiota-Associated Mice
T2 - A Model with Challenges
AU - Arrieta, Marie Claire
AU - Walter, Jens
AU - Finlay, B. Brett
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/5/11
Y1 - 2016/5/11
N2 - Human microbiota-associated (HMA) mice have been used extensively in gut microbiome research. Here we discuss ecological and evolutionary aspects of the mammalian-gut microbiome interrelationship that confound the application of HMA mice, and propose experimental designs that increase the likelihood for obtaining meaningful findings.
AB - Human microbiota-associated (HMA) mice have been used extensively in gut microbiome research. Here we discuss ecological and evolutionary aspects of the mammalian-gut microbiome interrelationship that confound the application of HMA mice, and propose experimental designs that increase the likelihood for obtaining meaningful findings.
UR - https://www.scopus.com/pages/publications/84969504890
U2 - 10.1016/j.chom.2016.04.014
DO - 10.1016/j.chom.2016.04.014
M3 - Comment/Debate
C2 - 27173924
AN - SCOPUS:84969504890
SN - 1931-3128
VL - 19
SP - 575
EP - 578
JO - Cell Host and Microbe
JF - Cell Host and Microbe
IS - 5
ER -
