Human Microbiota-Associated Mice: A Model with Challenges

Marie Claire Arrieta; Jens Walter; B. Brett Finlay

doi:10.1016/j.chom.2016.04.014

Human Microbiota-Associated Mice: A Model with Challenges

Marie Claire Arrieta
, Jens Walter
, B. Brett Finlay

Research output: Contribution to journal › Comment/Debate

Abstract

Human microbiota-associated (HMA) mice have been used extensively in gut microbiome research. Here we discuss ecological and evolutionary aspects of the mammalian-gut microbiome interrelationship that confound the application of HMA mice, and propose experimental designs that increase the likelihood for obtaining meaningful findings.

Original language	English
Pages (from-to)	575-578
Number of pages	4
Journal	Cell Host and Microbe
Volume	19
Issue number	5
DOIs	https://doi.org/10.1016/j.chom.2016.04.014
Publication status	Published - 11 May 2016
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.chom.2016.04.014

Cite this

@article{c0921641fe344ed99c034c1365edf4bf,

title = "Human Microbiota-Associated Mice: A Model with Challenges",

abstract = "Human microbiota-associated (HMA) mice have been used extensively in gut microbiome research. Here we discuss ecological and evolutionary aspects of the mammalian-gut microbiome interrelationship that confound the application of HMA mice, and propose experimental designs that increase the likelihood for obtaining meaningful findings.",

author = "Arrieta, \{Marie Claire\} and Jens Walter and Finlay, \{B. Brett\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = may,

day = "11",

doi = "10.1016/j.chom.2016.04.014",

language = "English",

volume = "19",

pages = "575--578",

journal = "Cell Host and Microbe",

issn = "1931-3128",

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number = "5",

}

TY - JOUR

T1 - Human Microbiota-Associated Mice

T2 - A Model with Challenges

AU - Arrieta, Marie Claire

AU - Walter, Jens

AU - Finlay, B. Brett

PY - 2016/5/11

Y1 - 2016/5/11

N2 - Human microbiota-associated (HMA) mice have been used extensively in gut microbiome research. Here we discuss ecological and evolutionary aspects of the mammalian-gut microbiome interrelationship that confound the application of HMA mice, and propose experimental designs that increase the likelihood for obtaining meaningful findings.

AB - Human microbiota-associated (HMA) mice have been used extensively in gut microbiome research. Here we discuss ecological and evolutionary aspects of the mammalian-gut microbiome interrelationship that confound the application of HMA mice, and propose experimental designs that increase the likelihood for obtaining meaningful findings.

UR - https://www.scopus.com/pages/publications/84969504890

U2 - 10.1016/j.chom.2016.04.014

DO - 10.1016/j.chom.2016.04.014

M3 - Comment/Debate

C2 - 27173924

AN - SCOPUS:84969504890

SN - 1931-3128

VL - 19

SP - 575

EP - 578

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 5

ER -

Human Microbiota-Associated Mice: A Model with Challenges

Abstract

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