TY - JOUR
T1 - In-Hospital Adverse Drug Reactions in Hospitalised Older Adults - A Systematic Review
AU - Jennings, Emma
AU - Murphy, Kevin
AU - Gallagher, Paul
AU - O'Mahony, Denis
PY - 2018
Y1 - 2018
N2 - Background: Recent studies indicate that 1 in 4 older people experience an ADR in hospital. This systematic review [SR] aims to evaluate in-hospital ADRs in hospitalised older-adults in terms of incidence and prevalence, most commonly involved drug classes, severity, and consequences.Methods: Using PRISMA methodology [PROSPERO registration CRD42018079095], we systematically searched PubMed, Embase and Ebsco-CINAHL, Cochrane Library and library hosted academic sources, Google® scholar, and ‘grey’ literature. Search terms included aged, ADRs, hospitalized, multi-morbid, polypharmacy and hospital-acquired. A hand search of bibliography lists from relevant editorials and systematic reviews was conducted. We included studies of all languages and all dates up to and including the date of the final search [15/01/2018]. We included all studies that reported ADRs either as a primary or secondary outcome in patients aged ≥ 65 years who were hospitalised at time of ADR occurrence. Two researchers screened all papers for inclusion, risk of bias and data extraction.
AB - Background: Recent studies indicate that 1 in 4 older people experience an ADR in hospital. This systematic review [SR] aims to evaluate in-hospital ADRs in hospitalised older-adults in terms of incidence and prevalence, most commonly involved drug classes, severity, and consequences.Methods: Using PRISMA methodology [PROSPERO registration CRD42018079095], we systematically searched PubMed, Embase and Ebsco-CINAHL, Cochrane Library and library hosted academic sources, Google® scholar, and ‘grey’ literature. Search terms included aged, ADRs, hospitalized, multi-morbid, polypharmacy and hospital-acquired. A hand search of bibliography lists from relevant editorials and systematic reviews was conducted. We included studies of all languages and all dates up to and including the date of the final search [15/01/2018]. We included all studies that reported ADRs either as a primary or secondary outcome in patients aged ≥ 65 years who were hospitalised at time of ADR occurrence. Two researchers screened all papers for inclusion, risk of bias and data extraction.
UR - https://cora.ucc.ie/items/af08e4a5-66d5-4f2a-bf80-16d62db920e0
U2 - 10.1007/s41999-018-0097-4
DO - 10.1007/s41999-018-0097-4
M3 - Meeting abstract
SN - 1878-7649
VL - 9
SP - S62
JO - European Geriatric Medicine
JF - European Geriatric Medicine
ER -