Inflammatory regulation of stem-like cells in melanoma

Ming Sheng Lim; Jiang Huai Wang; Derek G. Power; H. Paul Redmond

doi:10.1097/CMR.0000000000000303

Inflammatory regulation of stem-like cells in melanoma

Ming Sheng Lim
, Jiang Huai Wang
, Derek G. Power
, H. Paul Redmond

School of Medicine

University College Cork

Research output: Contribution to journal › Review article › peer-review

Abstract

The link between inflammation, immunity and cancer is well established. In the last decade, there has been considerable excitement over cancer stem cells, believed to be a subset of tumour cells responsible for their initiation, propagation and resistance to conventional chemoradiotherapy. In this review, we discuss the characterization of cancer stem cells and describe their modulation by inflammation with a focus on melanoma.

Original language	English
Pages (from-to)	1-7
Number of pages	7
Journal	Melanoma Research
Volume	27
Issue number	1
DOIs	https://doi.org/10.1097/CMR.0000000000000303
Publication status	Published - 2017

Keywords

Inflammation
Melanoma
Phenotype switch
Stem cell
Tumour-initiating cell

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/CMR.0000000000000303

Cite this

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title = "Inflammatory regulation of stem-like cells in melanoma",

abstract = "The link between inflammation, immunity and cancer is well established. In the last decade, there has been considerable excitement over cancer stem cells, believed to be a subset of tumour cells responsible for their initiation, propagation and resistance to conventional chemoradiotherapy. In this review, we discuss the characterization of cancer stem cells and describe their modulation by inflammation with a focus on melanoma.",

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AU - Lim, Ming Sheng

AU - Wang, Jiang Huai

AU - Power, Derek G.

AU - Redmond, H. Paul

PY - 2017

Y1 - 2017

N2 - The link between inflammation, immunity and cancer is well established. In the last decade, there has been considerable excitement over cancer stem cells, believed to be a subset of tumour cells responsible for their initiation, propagation and resistance to conventional chemoradiotherapy. In this review, we discuss the characterization of cancer stem cells and describe their modulation by inflammation with a focus on melanoma.

AB - The link between inflammation, immunity and cancer is well established. In the last decade, there has been considerable excitement over cancer stem cells, believed to be a subset of tumour cells responsible for their initiation, propagation and resistance to conventional chemoradiotherapy. In this review, we discuss the characterization of cancer stem cells and describe their modulation by inflammation with a focus on melanoma.

KW - Inflammation

KW - Melanoma

KW - Phenotype switch

KW - Stem cell

KW - Tumour-initiating cell

UR - https://www.scopus.com/pages/publications/84992121167

U2 - 10.1097/CMR.0000000000000303

DO - 10.1097/CMR.0000000000000303

M3 - Review article

C2 - 27764061

AN - SCOPUS:84992121167

SN - 0960-8931

VL - 27

SP - 1

EP - 7

JO - Melanoma Research

JF - Melanoma Research

IS - 1

ER -

Inflammatory regulation of stem-like cells in melanoma

Abstract

Keywords

UN SDGs

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