Influence of the gut microbiota with ageing

E. Murphy; C. Murphy; L. O'Mahony

doi:10.1007/978-1-59745-327-1_8

Influence of the gut microbiota with ageing

E. Murphy
, C. Murphy
, L. O'Mahony

University College Cork

Research output: Chapter in Book/Report/Conference proceedings › Chapter › peer-review

Abstract

The mucosal surface of the human gastrointestinal tract is approximately 200-300 m² in area and is colonized by 10(13-14) bacteria of greater than 1,000 different species and subspecies. The number of bacterial cells within the gastrointestinal tract outnumbers the host cell populations by 10:1, highlighting the relative importance of microbiota composition and metabolic activity on host homeostasis.¹ This review will discuss some of the better described microbiota-related activities that influence host function and the relationship with host ageing. However, most of the bacterial species present within the gastrointestinal tract still remain to be characterized, and many of the mechanisms underpinning their activities remain unexplored.

Original language	English
Title of host publication	Microbiology and Aging
Subtitle of host publication	Clinical Manifestations
Publisher	Humana Press
Pages	153-173
Number of pages	21
ISBN (Print)	9781588296405
DOIs	https://doi.org/10.1007/978-1-59745-327-1_8
Publication status	Published - 2009

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Influence of the gut microbiota with ageing

Abstract

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