Insertional mutagenesis to generate lantibiotic resistance in Lactococcus lactis

Caitriona M. Guinane; Paul D. Cotter; Elaine M. Lawton; Colin Hill; R. Paul Ross

doi:10.1128/AEM.02351-06

Insertional mutagenesis to generate lantibiotic resistance in Lactococcus lactis

Caitriona M. Guinane
, Paul D. Cotter
, Elaine M. Lawton
, Colin Hill
, R. Paul Ross

Research output: Contribution to journal › Article › peer-review

Abstract

While the potential emergence of food spoilage and pathogenic bacteria with resistance to lantibiotics is a concern, the creation of derivatives of starter cultures and adjuncts that can grow in the presence of these antimicrobials may have applications in food fermentations. Here a bank of Lactococcus lactis IL1403 mutants was created and screened, and a number of novel genetic loci involved in lantibiotic resistance were identified.

Original language	English
Pages (from-to)	4677-4680
Number of pages	4
Journal	Applied and Environmental Microbiology
Volume	73
Issue number	14
DOIs	https://doi.org/10.1128/AEM.02351-06
Publication status	Published - Jul 2007

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abstract = "While the potential emergence of food spoilage and pathogenic bacteria with resistance to lantibiotics is a concern, the creation of derivatives of starter cultures and adjuncts that can grow in the presence of these antimicrobials may have applications in food fermentations. Here a bank of Lactococcus lactis IL1403 mutants was created and screened, and a number of novel genetic loci involved in lantibiotic resistance were identified.",

author = "Guinane, \{Caitriona M.\} and Cotter, \{Paul D.\} and Lawton, \{Elaine M.\} and Colin Hill and Ross, \{R. Paul\}",

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AU - Guinane, Caitriona M.

AU - Cotter, Paul D.

AU - Lawton, Elaine M.

AU - Hill, Colin

AU - Ross, R. Paul

PY - 2007/7

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AB - While the potential emergence of food spoilage and pathogenic bacteria with resistance to lantibiotics is a concern, the creation of derivatives of starter cultures and adjuncts that can grow in the presence of these antimicrobials may have applications in food fermentations. Here a bank of Lactococcus lactis IL1403 mutants was created and screened, and a number of novel genetic loci involved in lantibiotic resistance were identified.

UR - https://www.scopus.com/pages/publications/34547152043

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DO - 10.1128/AEM.02351-06

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AN - SCOPUS:34547152043

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SP - 4677

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JO - Applied and Environmental Microbiology

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Insertional mutagenesis to generate lantibiotic resistance in Lactococcus lactis

Abstract

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