Integrated system for interstitial photodynamic therapy

Stefan Andersson-Engels; Niels Bendsoe; Ann Johansson; Thomas Johansson; Sara Pålsson; Marcelo Soto Thompson; Unne Stenram; Katarina Svanberg; Sune Svanberg

doi:10.1117/12.500780

Integrated system for interstitial photodynamic therapy

Stefan Andersson-Engels
, Niels Bendsoe
, Ann Johansson
, Thomas Johansson
, Sara Pålsson
, Marcelo Soto Thompson
, Unne Stenram
, Katarina Svanberg
, Sune Svanberg

Lund University

Research output: Contribution to journal › Article › peer-review

Abstract

A novel photodynamic therapy system based on interstitial illumination using multiple fibres is under development. The aim with this system is to enable treatment of large tumour volumes and also to utilise real-time measurements to allow on-line dosimetry. Important dosimetric parameters to measure are light fluence rate, sensitizer fluorescence intensity and local blood oxygenation. A construction which allows all functions to be readily performed with a single system is presented. We believe that interstitial PDT utilising this technique may be attractive in many clinical situations.

Original language	English
Pages (from-to)	42-49
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5142
DOIs	https://doi.org/10.1117/12.500780
Publication status	Published - 2003
Externally published	Yes
Event	Therapeutic Laser Applications and Laser-Tissue Interactions - Munich, Germany Duration: 24 Jun 2003 → 25 Jun 2003

Keywords

Dosimetry
Fluorescence
Interstitial photodynamic therapy
Tissue optics

Access to Document

10.1117/12.500780

Cite this

@article{affdcc7538da44eca6539c8b790186d9,

title = "Integrated system for interstitial photodynamic therapy",

abstract = "A novel photodynamic therapy system based on interstitial illumination using multiple fibres is under development. The aim with this system is to enable treatment of large tumour volumes and also to utilise real-time measurements to allow on-line dosimetry. Important dosimetric parameters to measure are light fluence rate, sensitizer fluorescence intensity and local blood oxygenation. A construction which allows all functions to be readily performed with a single system is presented. We believe that interstitial PDT utilising this technique may be attractive in many clinical situations.",

keywords = "Dosimetry, Fluorescence, Interstitial photodynamic therapy, Tissue optics",

author = "Stefan Andersson-Engels and Niels Bendsoe and Ann Johansson and Thomas Johansson and Sara P{\aa}lsson and Thompson, \{Marcelo Soto\} and Unne Stenram and Katarina Svanberg and Sune Svanberg",

year = "2003",

doi = "10.1117/12.500780",

language = "English",

volume = "5142",

pages = "42--49",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Therapeutic Laser Applications and Laser-Tissue Interactions ; Conference date: 24-06-2003 Through 25-06-2003",

}

TY - JOUR

T1 - Integrated system for interstitial photodynamic therapy

AU - Andersson-Engels, Stefan

AU - Bendsoe, Niels

AU - Johansson, Ann

AU - Johansson, Thomas

AU - Pålsson, Sara

AU - Thompson, Marcelo Soto

AU - Stenram, Unne

AU - Svanberg, Katarina

AU - Svanberg, Sune

PY - 2003

Y1 - 2003

N2 - A novel photodynamic therapy system based on interstitial illumination using multiple fibres is under development. The aim with this system is to enable treatment of large tumour volumes and also to utilise real-time measurements to allow on-line dosimetry. Important dosimetric parameters to measure are light fluence rate, sensitizer fluorescence intensity and local blood oxygenation. A construction which allows all functions to be readily performed with a single system is presented. We believe that interstitial PDT utilising this technique may be attractive in many clinical situations.

AB - A novel photodynamic therapy system based on interstitial illumination using multiple fibres is under development. The aim with this system is to enable treatment of large tumour volumes and also to utilise real-time measurements to allow on-line dosimetry. Important dosimetric parameters to measure are light fluence rate, sensitizer fluorescence intensity and local blood oxygenation. A construction which allows all functions to be readily performed with a single system is presented. We believe that interstitial PDT utilising this technique may be attractive in many clinical situations.

KW - Dosimetry

KW - Fluorescence

KW - Interstitial photodynamic therapy

KW - Tissue optics

UR - https://www.scopus.com/pages/publications/1342309841

U2 - 10.1117/12.500780

DO - 10.1117/12.500780

M3 - Article

AN - SCOPUS:1342309841

SN - 0277-786X

VL - 5142

SP - 42

EP - 49

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Therapeutic Laser Applications and Laser-Tissue Interactions

Y2 - 24 June 2003 through 25 June 2003

ER -

Integrated system for interstitial photodynamic therapy

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this