TY - GEN
T1 - Integrating sphere measurements of tissue optical properties for accurate photodynamic therapy (PDT) dosimetry
AU - Nilsson, Annika M.
AU - Berg, Roger
AU - Andersson-Engels, Stefan
N1 - Publisher Copyright:
© COPYRIGHT SPIE.
PY - 1995/1/18
Y1 - 1995/1/18
N2 - A set-up with an integrating sphere and a narrow-beam arrangement was used in order to derive the optical properties in vitro of 1 mm thick tissue slabs. The measured macroscopic quantities, the reflectance, and the total transmittance were correlated to the tissue optical properties by Monte Carlo simulations. Mie calculations were performed to be able to calibrate the set-up with a solution of latex spheres and ink. Finally, the optical properties of rat liver samples were measured, before and after photodynamic therapy, showing approximately a 40% increase of the absorption coefficient at 650 nm due to the treatment.
AB - A set-up with an integrating sphere and a narrow-beam arrangement was used in order to derive the optical properties in vitro of 1 mm thick tissue slabs. The measured macroscopic quantities, the reflectance, and the total transmittance were correlated to the tissue optical properties by Monte Carlo simulations. Mie calculations were performed to be able to calibrate the set-up with a solution of latex spheres and ink. Finally, the optical properties of rat liver samples were measured, before and after photodynamic therapy, showing approximately a 40% increase of the absorption coefficient at 650 nm due to the treatment.
UR - https://www.scopus.com/pages/publications/6344268486
U2 - 10.1117/12.199183
DO - 10.1117/12.199183
M3 - Conference proceeding
AN - SCOPUS:6344268486
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 47
EP - 57
BT - Laser Interaction with Hard and Soft Tissue II
A2 - Meier, Thomas H.
A2 - Albrecht, Hans Joerg
A2 - van Gemert, Martin J. C.
A2 - Steiner, Rudolf W.
A2 - Svaasand, Lars Othar
A2 - Delacretaz, Guy P.
PB - SPIE
T2 - Laser Interaction with Hard and Soft Tissue II 1994
Y2 - 6 September 1994 through 10 September 1994
ER -