Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia

Robert P. Ryan; Yvonne McCarthy; Steven A. Watt; Karsten Niehaus; J. Maxwell Dow

doi:10.1128/JB.00473-09

Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia

Robert P. Ryan
, Yvonne McCarthy
, Steven A. Watt
, Karsten Niehaus
, J. Maxwell Dow

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDSF also acts as an intraspecies signal in B. cenocepacia to control factors contributing to virulence of this major opportunistic pathogen.

Original language	English
Pages (from-to)	5013-5019
Number of pages	7
Journal	Journal of Bacteriology
Volume	191
Issue number	15
DOIs	https://doi.org/10.1128/JB.00473-09
Publication status	Published - Aug 2009

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title = "Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia",

abstract = "Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDSF also acts as an intraspecies signal in B. cenocepacia to control factors contributing to virulence of this major opportunistic pathogen.",

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AU - Watt, Steven A.

AU - Niehaus, Karsten

AU - Dow, J. Maxwell

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AB - Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDSF also acts as an intraspecies signal in B. cenocepacia to control factors contributing to virulence of this major opportunistic pathogen.

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ER -

Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia

Abstract

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