Lab-on-a-chip (LOC) immunoassays

Sandeep K. Vashist; John H.T. Luong

doi:10.1016/B978-0-12-811762-0.00015-3

Lab-on-a-chip (LOC) immunoassays

Sandeep K. Vashist
, John H.T. Luong

School of Chemistry

IDS Immunodiagnostic Systems Deutschland GmbH

Research output: Chapter in Book/Report/Conference proceedings › Chapter › peer-review

Abstract

The last two decades have witnessed numerous advances in lab-on-a-chip (LOC) platforms-based immunoassays (IAs). Such developed LOC platforms are diversified and comprise microfluidic chips, paper, lateral flow, cellphone, electrochemistry, and new biosensor concepts. In particular, the development of point-of-care testing devices for developing countries and remote settings has received significant attention. There are novel IA concepts and strategies for prolonged reagent storage and a significant progress in the achievement of next-generation automated, cost-effective, and easy-to-use LOC IAs. Nevertheless, some key technical issues must be addressed for the development of robust and clinically viable LOC-based IAs.

Original language	English
Title of host publication	Handbook of Immunoassay Technologies
Subtitle of host publication	Approaches, Performances, and Applications
Publisher	Elsevier
Pages	415-431
Number of pages	17
ISBN (Electronic)	9780128117620
ISBN (Print)	9780128117941
DOIs	https://doi.org/10.1016/B978-0-12-811762-0.00015-3
Publication status	Published - 1 Jan 2018

Keywords

Cellphone
Immunoassay formats
Lab-on-a-chip
Microfluidics
Paper

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10.1016/B978-0-12-811762-0.00015-3

Cite this

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N2 - The last two decades have witnessed numerous advances in lab-on-a-chip (LOC) platforms-based immunoassays (IAs). Such developed LOC platforms are diversified and comprise microfluidic chips, paper, lateral flow, cellphone, electrochemistry, and new biosensor concepts. In particular, the development of point-of-care testing devices for developing countries and remote settings has received significant attention. There are novel IA concepts and strategies for prolonged reagent storage and a significant progress in the achievement of next-generation automated, cost-effective, and easy-to-use LOC IAs. Nevertheless, some key technical issues must be addressed for the development of robust and clinically viable LOC-based IAs.

AB - The last two decades have witnessed numerous advances in lab-on-a-chip (LOC) platforms-based immunoassays (IAs). Such developed LOC platforms are diversified and comprise microfluidic chips, paper, lateral flow, cellphone, electrochemistry, and new biosensor concepts. In particular, the development of point-of-care testing devices for developing countries and remote settings has received significant attention. There are novel IA concepts and strategies for prolonged reagent storage and a significant progress in the achievement of next-generation automated, cost-effective, and easy-to-use LOC IAs. Nevertheless, some key technical issues must be addressed for the development of robust and clinically viable LOC-based IAs.

KW - Cellphone

KW - Immunoassay formats

KW - Lab-on-a-chip

KW - Microfluidics

KW - Paper

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BT - Handbook of Immunoassay Technologies

PB - Elsevier

ER -

Lab-on-a-chip (LOC) immunoassays

Abstract

Keywords

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