Liquid phantoms for near-infrared and diffuse correlation spectroscopies with tunable optical and dynamic properties

  • Lorenzo Cortese
  • , Giuseppe Lo Presti
  • , Marco Pagliazzi
  • , Davide Contini
  • , Alberto Dalla Mora
  • , Antonio Pifferi
  • , Sanathana Konugolu Venkata Sekar
  • , Lorenzo Spinelli
  • , Paola Taroni
  • , Marta Zanoletti
  • , Udo M. Weigel
  • , Sixte De Fraguier
  • , An Nguyen-Dihn
  • , Bogdan Rosinski
  • , Turgut Durduran

Research output: Contribution to journalArticlepeer-review

Abstract

We present the recipe and characterization for preparing liquid phantoms that are suitable for both near-infrared spectroscopy and diffuse correlation spectroscopy. The phantoms have well-defined and tunable optical and dynamic properties, and consist of a solution of water and glycerol with fat emulsion as the scattering element. The recipe takes into account the effect of bulk refractive index changes due to the addition of glycerol, which is commonly used to alter the sample viscosity.

Original languageEnglish
Article number#321229
Pages (from-to)2068-2080
Number of pages13
JournalBiomedical Optics Express
Volume9
Issue number5
DOIs
Publication statusPublished - 1 May 2018
Externally publishedYes

Keywords

  • Diffusion
  • Light propagation in tissues
  • Scattering
  • Spectroscopy, speckle

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