Macrolide resistance mediated by a Bifidobacterium breve membrane protein

  • Abelardo Margolles
  • , José Antonio Moreno
  • , Douwe Van Sinderen
  • , Clara G. De Los Reyes-Gavilân

Research output: Contribution to journalArticlepeer-review

Abstract

A gene coding for a hypothetical membrane protein from Bifidobacterium breve was expressed in Lactococcus lactis. Immunoblotting demonstrated that this protein is located in the membrane. Phenotypical changes in sensitivity towards 21 antibiotics were determined. The membrane protein-expressing cells showed higher levels of resistance to several macrolides.

Original languageEnglish
Pages (from-to)4379-4381
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume49
Issue number10
DOIs
Publication statusPublished - Oct 2005

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