Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

Marco Candela; Elena Biagi; Patrizia Brigidi; Paul W. O'Toole; Willem M. De Vos

doi:10.1016/j.mad.2013.12.004

Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

Marco Candela
, Elena Biagi
, Patrizia Brigidi
, Paul W. O'Toole
, Willem M. De Vos

Research output: Contribution to journal › Article › peer-review

Abstract

Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging.

Original language	English
Pages (from-to)	70-75
Number of pages	6
Journal	Mechanisms of Ageing and Development
Volume	136-137
DOIs	https://doi.org/10.1016/j.mad.2013.12.004
Publication status	Published - Mar 2014

Keywords

Diet
Frailty
Healthy aging
Inflammation
Intestinal microbiota

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10.1016/j.mad.2013.12.004

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abstract = "Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging.",

keywords = "Diet, Frailty, Healthy aging, Inflammation, Intestinal microbiota",

author = "Marco Candela and Elena Biagi and Patrizia Brigidi and O'Toole, \{Paul W.\} and \{De Vos\}, \{Willem M.\}",

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T1 - Maintenance of a healthy trajectory of the intestinal microbiome during aging

T2 - A dietary approach

AU - Candela, Marco

AU - Biagi, Elena

AU - Brigidi, Patrizia

AU - O'Toole, Paul W.

AU - De Vos, Willem M.

PY - 2014/3

Y1 - 2014/3

N2 - Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging.

AB - Sharing an intense transgenomic metabolism with the host, the intestinal microbiota is an essential factor for several aspects of the human physiology. However, several age-related factors, such as changes diet, lifestyle, inflammation and frailty, force the deterioration of this intestinal microbiota-host mutualistic interaction, compromising the possibility to reach longevity. In this scenario, the NU-AGE project involves the development of dietary interventions specifically tailored to the maintenance of a healthy trajectory of the intestinal microbiome, counteracting all processes connected to the pathophysiology of the human aging.

KW - Diet

KW - Frailty

KW - Healthy aging

KW - Inflammation

KW - Intestinal microbiota

UR - https://www.scopus.com/pages/publications/84899941964

U2 - 10.1016/j.mad.2013.12.004

DO - 10.1016/j.mad.2013.12.004

M3 - Article

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AN - SCOPUS:84899941964

SN - 0047-6374

VL - 136-137

SP - 70

EP - 75

JO - Mechanisms of Ageing and Development

JF - Mechanisms of Ageing and Development

ER -

Maintenance of a healthy trajectory of the intestinal microbiome during aging: A dietary approach

Abstract

Keywords

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