TY - JOUR
T1 - Management of tubal ectopic pregnancy in a large maternity unit; a six-year review
AU - Synnott, D.
AU - Leitao, S.
AU - Everard, C.
AU - Donoghue, K. O.’.
AU - Hayes-Ryan, D.
N1 - Publisher Copyright:
© 2025 Elsevier B.V.
PY - 2025/4/17
Y1 - 2025/4/17
N2 - Objective(s): Ectopic pregnancy is where a pregnancy develops in an abnormal location. The incidence of ectopic pregnancy in Ireland is approximately 14.8 per 1,000 maternities. Most occur within the fallopian tube and untreated may result in serious morbidity with complications including blood transfusion, visceral injury at surgery and death. Ectopic pregnancy remains the leading cause of death worldwide in the first trimester of pregnancy. We aimed to examine the diagnosis and management of tubal ectopic pregnancy in a large tertiary maternity hospital. Study Design: This was a retrospective review of individuals treated for tubal ectopic pregnancy from 2017 to 2022. Records were identified from local databases. Anonymised data on risk-factors, symptoms and management was collected. Data were transcribed from electronic healthcare records and descriptive analyses performed. Results: Of the 471 records identified; 20 were excluded as they were non-tubal ectopic pregnancies. Primary management employed was conservative (99/451, 22 %), medical (113/451, 25 %) and surgical (239/451, 53 %). Surgery was performed in 62.7 % (283/451) cases, including those who started in one treatment pathway but changed to surgical management. Most surgeries were performed in a co-located general hospital theatre (89.3 %), with 54.4 % undertaken out-of-hours. Laparoscopy was the commonest surgical approach (96.4 %) and salpingectomy the most prevalent procedure (99.3 %). Emergency surgical intervention, due to haemodynamic instability and/or suspected rupture, was required in 21.9% (62/283). Only 11.7% (33/283) of those managed surgically experienced adverse outcomes, with blood transfusion and high dependency unit admission the most common. A small proportion (10%) of individuals were provided with pregnancy loss information (including resources and support services available), highlighting the importance of recognising ectopic pregnancy as a pregnancy loss and not just a gynaecological emergency. Conclusion(s): In this large series, most tubal ectopic pregnancies had surgical laparoscopic management, but this was outside normal working hours and in a co-located general hospital. Management of tubal ectopic pregnancy was safe with minimal adverse outcomes.
AB - Objective(s): Ectopic pregnancy is where a pregnancy develops in an abnormal location. The incidence of ectopic pregnancy in Ireland is approximately 14.8 per 1,000 maternities. Most occur within the fallopian tube and untreated may result in serious morbidity with complications including blood transfusion, visceral injury at surgery and death. Ectopic pregnancy remains the leading cause of death worldwide in the first trimester of pregnancy. We aimed to examine the diagnosis and management of tubal ectopic pregnancy in a large tertiary maternity hospital. Study Design: This was a retrospective review of individuals treated for tubal ectopic pregnancy from 2017 to 2022. Records were identified from local databases. Anonymised data on risk-factors, symptoms and management was collected. Data were transcribed from electronic healthcare records and descriptive analyses performed. Results: Of the 471 records identified; 20 were excluded as they were non-tubal ectopic pregnancies. Primary management employed was conservative (99/451, 22 %), medical (113/451, 25 %) and surgical (239/451, 53 %). Surgery was performed in 62.7 % (283/451) cases, including those who started in one treatment pathway but changed to surgical management. Most surgeries were performed in a co-located general hospital theatre (89.3 %), with 54.4 % undertaken out-of-hours. Laparoscopy was the commonest surgical approach (96.4 %) and salpingectomy the most prevalent procedure (99.3 %). Emergency surgical intervention, due to haemodynamic instability and/or suspected rupture, was required in 21.9% (62/283). Only 11.7% (33/283) of those managed surgically experienced adverse outcomes, with blood transfusion and high dependency unit admission the most common. A small proportion (10%) of individuals were provided with pregnancy loss information (including resources and support services available), highlighting the importance of recognising ectopic pregnancy as a pregnancy loss and not just a gynaecological emergency. Conclusion(s): In this large series, most tubal ectopic pregnancies had surgical laparoscopic management, but this was outside normal working hours and in a co-located general hospital. Management of tubal ectopic pregnancy was safe with minimal adverse outcomes.
KW - Early pregnancy loss
KW - Maternal morbidity
KW - Methotrexate
KW - Surgical management of ectopic pregnancy
KW - Tubal ectopic pregnancy
UR - https://www.scopus.com/pages/publications/86000578678
U2 - 10.1016/j.ejogrb.2025.02.058
DO - 10.1016/j.ejogrb.2025.02.058
M3 - Article
C2 - 40073754
AN - SCOPUS:86000578678
SN - 0301-2115
VL - 308
SP - 174
EP - 180
JO - European Journal of Obstetrics and Gynecology and Reproductive Biology
JF - European Journal of Obstetrics and Gynecology and Reproductive Biology
ER -